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Enhancing biopolymer hydrogel functionality through interpenetrating networks
Traditional hydrogels are strong candidates for biomedical applications; however, they may
suffer from drawbacks such as weak mechanics, static properties, and an inability to fully …
suffer from drawbacks such as weak mechanics, static properties, and an inability to fully …
Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip
Significant advances in materials, microscale technology, and stem cell biology have
enabled the construction of 3D tissues and organs, which will ultimately lead to more …
enabled the construction of 3D tissues and organs, which will ultimately lead to more …
Standardizing designed and emergent quantitative features in microphysiological systems
DM Nahon, R Moerkens, H Aydogmus… - Nature biomedical …, 2024 - nature.com
Microphysiological systems (MPSs) are cellular models that replicate aspects of organ and
tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide …
tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide …
From arteries to capillaries: approaches to engineering human vasculature
From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …
scales and cell types. The convergence of bioengineering, materials science, and stem cell …
Advances in microfluidic blood–brain barrier (BBB) models
Therapeutic options for neurological disorders currently remain limited. The intrinsic
complexity of the brain architecture prevents potential therapeutics from reaching their …
complexity of the brain architecture prevents potential therapeutics from reaching their …
Microfluidic tissue engineering and bio‐actuation
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
Organ‐on‐a‐chip for cancer and immune organs modeling
Bridging the gap between findings in preclinical 2D cell culture models and in vivo tissue
cultures has been challenging; the simple microenvironment of 2D monolayer culture …
cultures has been challenging; the simple microenvironment of 2D monolayer culture …
Engineering of hydrogel materials with perfusable microchannels for building vascularized tissues
R **e, W Zheng, L Guan, Y Ai, Q Liang - Small, 2020 - Wiley Online Library
Vascular systems are responsible for various physiological and pathological processes
related to all organs in vivo, and the survival of engineered tissues for enough nutrient …
related to all organs in vivo, and the survival of engineered tissues for enough nutrient …
Coaxial cell printing of freestanding, perfusable, and functional in vitro vascular models for recapitulation of native vascular endothelium pathophysiology
Abstract 3D printing technology is used to produce channels within hydrogels followed by
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …
endothelial cells (ECs)‐seeding to establish in vitro vascular models. However, as built‐in …