Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grou** of interconnected brain …

Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …

Psilocybin has shown promise for the treatment of mood disorders, which are often
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …

The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …

Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …

Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …