Autoantibodies in neurological disease

H Prüss - Nature reviews immunology, 2021 - nature.com
The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …

Sleep, cerebrospinal fluid, and the glymphatic system: A systematic review

PLH Chong, D Garic, MD Shen, I Lundgaard… - Sleep medicine …, 2022 - Elsevier
Current theories of the glymphatic system (GS) hypothesize that it relies on cerebrospinal
fluid (CSF) circulation to disseminate growth factors and remove metabolic waste from the …

Origins and immunopathogenesis of autoimmune central nervous system disorders

S Ramanathan, F Brilot, SR Irani, RC Dale - Nature Reviews Neurology, 2023 - nature.com
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Cerebrospinal fluid findings in patients with autoimmune encephalitis—a systematic analysis

T Blinder, J Lewerenz - Frontiers in neurology, 2019 - frontiersin.org
Autoimmune encephalitides (AIE) comprise a group of inflammatory diseases of the central
nervous system (CNS), which can be further characterized by the presence of different …

Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease

T Grüter, FE Möllers, A Tietz, J Dargvainiene, N Melzer… - Brain, 2023 - academic.oup.com
Anti-IgLON5 disease is a newly defined clinical entity characterized by a progressive course
with high disability and mortality rate. While precise pathogenetic mechanisms remain …

Frequency and characterization of movement disorders in anti-IgLON5 disease

C Gaig, Y Compta, A Heidbreder, MJ Marti, MJ Titulaer… - Neurology, 2021 - neurology.org
Background and Objectives Anti-IgLON5 disease is a recently described neurologic disease
that shares features of autoimmunity and neurodegeneration. Abnormal movements appear …

HLA-DQB1* 05 subtypes and not DRB1* 10: 01 mediates risk in anti-IgLON5 disease

SM Yogeshwar, S Muñiz-Castrillo, L Sabater… - Brain, 2024 - academic.oup.com
Anti-IgLON5 disease is a rare and likely underdiagnosed subtype of autoimmune
encephalitis. The disease displays a heterogeneous phenotype that includes sleep …

Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease

E Berger-Sieczkowski, V Endmayr, C Haider… - Acta …, 2023 - Springer
Anti-IgLON5 disease is a rare neurological, probably autoimmune, disorder associated in
many cases with a specific tauopathy. Only a few post-mortem neuropathological studies …

REM sleep behavior disorder: diagnosis, clinical implications, and future directions

EK St Louis, BF Boeve - Mayo Clinic Proceedings, 2017 - Elsevier
Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of
dream enactment accompanied by polysomnographic rapid eye movement sleep atonia …

Sleep disorders in autoimmune encephalitis

A Muñoz-Lopetegi, F Graus, J Dalmau… - The Lancet …, 2020 - thelancet.com
Sleep disorders in people with autoimmune encephalitis have received little attention,
probably overshadowed by the presence of other neurological and psychiatric symptoms in …