Negative symptoms in schizophrenia: a review and clinical guide for recognition, assessment, and treatment
CU Correll, NR Schooler - Neuropsychiatric disease and treatment, 2020 - Taylor & Francis
Schizophrenia is frequently a chronic and disabling disorder, characterized by
heterogeneous positive and negative symptom constellations. The objective of this review …
heterogeneous positive and negative symptom constellations. The objective of this review …
The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies.
The reliability and validity of traditional taxonomies are limited by arbitrary boundaries
between psychopathology and normality, often unclear boundaries between disorders …
between psychopathology and normality, often unclear boundaries between disorders …
The clinical characterization of the patient with primary psychosis aimed at personalization of management
The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …
Negative symptoms of schizophrenia: new developments and unanswered research questions
Negative symptoms of schizophrenia are associated with poor functional outcome and place
a substantial burden on people with this disorder, their families, and health-care systems …
a substantial burden on people with this disorder, their families, and health-care systems …
EPA guidance on assessment of negative symptoms in schizophrenia
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …
brought about by the increased awareness that they interfere severely with real-life …
Validity and utility of hierarchical taxonomy of psychopathology (HiTOP): I. Psychosis superspectrum
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …
The current conceptualization of negative symptoms in schizophrenia
Negative symptoms have long been conceptualized as a core aspect of schizophrenia. They
play a key role in the functional outcome of the disorder, and their management represents a …
play a key role in the functional outcome of the disorder, and their management represents a …
A non–D2-receptor-binding drug for the treatment of schizophrenia
Background An oral compound, SEP-363856, that does not act on dopamine D2 receptors
but has agonist activity at trace amine–associated receptor 1 (TAAR1) and 5 …
but has agonist activity at trace amine–associated receptor 1 (TAAR1) and 5 …
Primary and secondary negative symptoms in schizophrenia
SN Mosolov, PA Yaltonskaya - Frontiers in psychiatry, 2022 - frontiersin.org
The negative symptoms of schizophrenia include volitional (motivational) impairment
manifesting as avolition, anhedonia, social withdrawal, and emotional disorders such as …
manifesting as avolition, anhedonia, social withdrawal, and emotional disorders such as …
Factors associated with real-life functioning in persons with schizophrenia in a 4-year follow-up study of the Italian network for research on psychoses
Importance The goal of schizophrenia treatment has shifted from symptom reduction and
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …