Tools for genomic and transcriptomic analysis of microbes at single-cell level

Z Chen, L Chen, W Zhang - Frontiers in microbiology, 2017 - frontiersin.org
Microbiologists traditionally study population rather than individual cells, as it is generally
assumed that the status of individual cells will be similar to that observed in the population …

Adaptive laboratory evolution of microbial co‐cultures for improved metabolite secretion

D Konstantinidis, F Pereira, EM Geissen… - Molecular systems …, 2021 - embopress.org
Adaptive laboratory evolution has proven highly effective for obtaining microorganisms with
enhanced capabilities. Yet, this method is inherently restricted to the traits that are positively …

Evolution on the bright side of life: microorganisms and the evolution of mutualism

KL Hillesland - Annals of the New York Academy of Sciences, 2018 - Wiley Online Library
Mutualistic interactions, where two interacting species have a net beneficial effect on each
other's fitness, play a crucial role in the survival and evolution of many species. Despite …

Microbial communities display alternative stable states in a fluctuating environment

CI Abreu, VL Andersen Woltz… - PLoS computational …, 2020 - journals.plos.org
The effect of environmental fluctuations is a major question in ecology. While it is widely
accepted that fluctuations and other types of disturbances can increase biodiversity, there …

The rate of environmental fluctuations shapes ecological dynamics in a two‐species microbial system

A Rodríguez‐Verdugo, C Vulin, M Ackermann - Ecology letters, 2019 - Wiley Online Library
Species interactions change when the external conditions change. How these changes
affect microbial community properties is an open question. We address this question using a …

Ocean acidification conditions increase resilience of marine diatoms

JJ Valenzuela, A López García de Lomana… - Nature …, 2018 - nature.com
The fate of diatoms in future acidified oceans could have dramatic implications on marine
ecosystems, because they account for~ 40% of marine primary production. Here, we …

Gene regulatory network topology governs resistance and treatment escape in glioma stem-like cells

JH Park, P Hothi, ALG de Lomana, M Pan, R Calder… - Science …, 2024 - science.org
Poor prognosis and drug resistance in glioblastoma (GBM) can result from cellular
heterogeneity and treatment-induced shifts in phenotypic states of tumor cells, including …

Microscale dynamics of dark zone alterations in anthropized karstic cave shows abrupt microbial community switch

Z Bontemps, M Hugoni, Y Moënne-Loccoz - Science of The Total …, 2023 - Elsevier
Strong anthropization of karstic caves may result in formation of various wall alterations
including dark zones, whose microbial community differs from that of non-altered surfaces …

Potential role of N-acyl homoserine lactone-mediated quorum sensing in the adaptation of anammox granular sludge system to salinity stress

P Gao, A Zhao, X Zhang, P Tang, D Li, T Liu, J Li… - Bioresource …, 2025 - Elsevier
Anammox granular sludge (AnGS) systems efficiently remove nitrogen from saline
wastewater, but their adaptation mechanisms to salt stress are unclear. This study explores …

Legacy of prior host and soil selection on rhizobial fitness in planta

LT Burghardt, B Epstein, P Tiffin - Evolution, 2019 - academic.oup.com
Measuring selection acting on microbial populations in natural or even seminatural
environments is challenging because many microbial populations experience variable …