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Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review
At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …
Synthesis and pharmacological properties of chalcones: a review
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …
research papers have been published, and chalcones continue to show promise for new …
[HTML][HTML] Pyrazoline hybrids as promising anticancer agents: An up-to-date overview
Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …
attracted significant attention from organic and medicinal chemists due to their potent …
Recent advances in the therapeutic applications of pyrazolines
MR Shaaban, AS Mayhoub… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Pyrazolines are well-known and important nitrogen-containing five-membered
ring heterocyclic compounds. Various methods have been worked out for their synthesis …
ring heterocyclic compounds. Various methods have been worked out for their synthesis …
Biological activities of pyrazoline derivatives-A recent development
Pyrazolines are well known and important nitrogen containing 5-membered heterocyclic
compounds and various methods have been worked out for their synthesis. Numerous …
compounds and various methods have been worked out for their synthesis. Numerous …
Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl) amino] chalcones and hydrazine as potential antitumor and antimalarial agents
A new series of N-acetyl and N-formyl-pyrazoline derivatives 6 and 7–8 were synthesized by
cyclocondensation reaction of [(7-chloroquinolin-4-yl) amino] chalcones with hydrazine …
cyclocondensation reaction of [(7-chloroquinolin-4-yl) amino] chalcones with hydrazine …
Synthesis and antimicrobial activity of novel quinoline derivatives bearing pyrazoline and pyridine analogues
The present investigation is in the interest of some synthesized novel derivatives containing
(5-(2-chloroquinolin-3-yl)-3-(aryl)-4, 5-dihydro-1 H-pyrazol-1-yl)(pyridin-4-yl) methanones …
(5-(2-chloroquinolin-3-yl)-3-(aryl)-4, 5-dihydro-1 H-pyrazol-1-yl)(pyridin-4-yl) methanones …
Efficient synthesis of chiral trisubstituted 1, 2‐allenyl ketones by catalytic asymmetric conjugate addition of malonic esters to enynes
Q Yao, Y Liao, L Lin, X Lin, J Ji, X Liu… - Angewandte Chemie …, 2016 - Wiley Online Library
Abstract An N, N′‐dioxide/scandium (III) complex catalyzed, highly efficient conjugate
addition of malonic esters to enynes is described. A range of trisubstituted 1, 2‐allenyl …
addition of malonic esters to enynes is described. A range of trisubstituted 1, 2‐allenyl …
Ultrasound‐Assisted Synthesis and Antioxidant Activity of 3‐Selanyl‐1 H‐indole and 3‐Selanylimidazo[1,2‐a]pyridine Derivatives
BM Vieira, S Thurow, M da Costa… - Asian Journal of …, 2017 - Wiley Online Library
A simple and rapid method for the selective synthesis of 3‐(organylselanyl)‐1 H‐indoles and
3‐(organylselanyl) imidazo [1, 2‐a] pyridines catalyzed by CuI/SeO2 under ultrasound …
3‐(organylselanyl) imidazo [1, 2‐a] pyridines catalyzed by CuI/SeO2 under ultrasound …