Cardiovascular risk in non-alcoholic fatty liver disease: mechanisms and therapeutic implications

C Tana, S Ballestri, F Ricci, A Di Vincenzo… - International journal of …, 2019 - mdpi.com
New evidence suggests that non-alcoholic fatty liver disease (NAFLD) has a strong
multifaceted relationship with diabetes and metabolic syndrome, and is associated with …

ACG clinical guideline: disorders of the hepatic and mesenteric circulation

DA Simonetto, AK Singal, G Garcia-Tsao… - Official journal of the …, 2020 - journals.lww.com
Disorders of the mesenteric, portal, and hepatic veins and mesenteric and hepatic arteries
have important clinical consequences and may lead to acute liver failure, chronic liver …

[HTML][HTML] Global hemostatic profiling in patients with decompensated cirrhosis and bacterial infections

A Zanetto, E Campello, C Bulato, S Gavasso… - JHEP Reports, 2022 - Elsevier
Background & Aims Bacterial infections in cirrhosis are associated with increased bleeding
risk. To assess the factors responsible for bleeding tendency in patients with bacterial …

[HTML][HTML] Anticoagulation in the cirrhotic patient

L Turco, E de Raucourt, DC Valla, E Villa - JHEP Reports, 2019 - Elsevier
In the past, patients with liver cirrhosis were thought to be prone to increased bleeding risk.
However, those with compensated liver cirrhosis actually have normal coagulative balance …

[HTML][HTML] Coagulation and endothelial dysfunction associated with NAFLD: current status and therapeutic implications

D Ogresta, A Mrzljak, MC Berkovic… - Journal of clinical and …, 2022 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is closely related to insulin resistance, type 2
diabetes mellitus and obesity. It is considered a multisystem disease and there is a strong …

NASHFit: A randomized controlled trial of an exercise training program to reduce clotting risk in patients with NASH

JG Stine, IR Schreibman, AJ Faust, J Dahmus… - …, 2022 - Wiley Online Library
Background and Aims NASH is a common disease associated with increased rates of
thromboembolism (TE). Although exercise training can lessen thrombotic risk in patients with …

Direct oral anticoagulants in patients with liver disease in the era of non-alcoholic fatty liver disease global epidemic: a narrative review

S Ballestri, M Capitelli, MC Fontana, D Arioli… - Advances in …, 2020 - Springer
Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent and relevant
healthcare issues. Direct oral anticoagulants (DOACs) are now the first-choice for …

[HTML][HTML] Procedural-related bleeding in hospitalized patients with liver disease (PROC-BLeeD): An international, prospective, multicenter observational study

NM Intagliata, RS Rahimi, F Higuera-de-la-Tijera… - Gastroenterology, 2023 - Elsevier
Background & Aims Hospitalized patients with cirrhosis frequently undergo multiple
procedures. The risk of procedural-related bleeding remains unclear, and management is …

Haemostatic profiles are similar across all aetiologies of cirrhosis

S Bos, B van den Boom… - Thrombosis and …, 2019 - thieme-connect.com
Background and Aim Patients with cirrhosis may acquire profound changes in haemostasis.
Although haemostatic changes in cirrhosis have been extensively studied, most studies …

Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease

OO Badmus, ZA Kipp, EA Bates… - American Journal …, 2023 - journals.physiology.org
The leading cause of death in patients with nonalcoholic fatty liver disease (NAFLD) is
cardiovascular disease (CVD). However, the mechanisms are unknown. Mice deficient in …