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Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
[HTML][HTML] Recent advances in tumor targeting via EPR effect for cancer treatment
Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …
Lymphatic vessels in bone support regeneration after injury
Blood and lymphatic vessels form a versatile transport network and provide inductive signals
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …
Nanomaterial delivery systems for mRNA vaccines
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …
development of lipid nanoparticle delivery systems that not only efficiently express the …
From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …
curtailing pandemic spread of emerging pathogens to which a population has limited …
Material design for lymph node drug delivery
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
Lymphatic vessels in cancer
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …
nodes that are present in almost every tissue of the human body, acts as an essential …
Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines
T Nakamura, Y Sato, Y Yamada… - Advanced drug delivery …, 2022 - Elsevier
A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
Nanoparticle vaccines against infectious diseases
R Pati, M Shevtsov, A Sonawane - Frontiers in immunology, 2018 - frontiersin.org
Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …
immunization of infectious diseases have become a great challenge in the past few years. In …
Pharmacokinetics of monoclonal antibodies
JT Ryman, B Meibohm - CPT: pharmacometrics & systems …, 2017 - Wiley Online Library
Monoclonal antibodies (mAbs) have developed in the last two decades into the backbone of
pharmacotherapeutic interventions in a variety of indications, with currently more than 40 …
pharmacotherapeutic interventions in a variety of indications, with currently more than 40 …