[HTML][HTML] Toll-like receptor 3 (TLR3) regulation mechanisms and roles in antiviral innate immune responses

C Yujuan, LIN Junhong, Z Yao… - Journal of Zhejiang …, 2021 - ncbi.nlm.nih.gov
Abstract Toll-like receptor 3 (TLR3) is a member of the TLR family, mediating the
transcriptional induction of type I interferons (IFNs), proinflammatory cytokines, and …

Biochemistry and molecular biology of flaviviruses

NJ Barrows, RK Campos, KC Liao, KR Prasanth… - Chemical …, 2018 - ACS Publications
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

The global ecology and epidemiology of West Nile virus

C Chancey, A Grinev, E Volkova… - BioMed research …, 2015 - Wiley Online Library
Since its initial isolation in Uganda in 1937 through the present, West Nile virus (WNV) has
become an important cause of human and animal disease worldwide. WNV, an enveloped …

Flavivirus NS1: a multifaceted enigmatic viral protein

M Rastogi, N Sharma, SK Singh - Virology journal, 2016 - Springer
Flaviviruses are emerging arthropod-borne viruses representing an immense global health
problem. The prominent viruses of this group include dengue virus, yellow fever virus …

The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

DA Muller, PR Young - Antiviral research, 2013 - Elsevier
The flavivirus nonstructural glycoprotein NS1 is an enigmatic protein whose structure and
mechanistic function have remained somewhat elusive ever since it was first reported in …

West Nile virus infection and immunity

MS Suthar, MS Diamond, M Gale Jr - Nature Reviews Microbiology, 2013 - nature.com
West Nile virus (WNV) is an emerging neurotropic flavivirus that is transmitted to humans
through the bite of an infected mosquito. WNV has disseminated broadly in the Western …

Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system

DL Akey, WC Brown, S Dutta, J Konwerski, J Jose… - Science, 2014 - science.org
Flaviviruses, the human pathogens responsible for dengue fever, West Nile fever, tick-borne
encephalitis, and yellow fever, are endemic in tropical and temperate parts of the world. The …

Viral evasion and subversion of pattern-recognition receptor signalling

AG Bowie, L Unterholzner - Nature Reviews Immunology, 2008 - nature.com
The expression of pattern-recognition receptors (PRRs) by immune and tissue cells provides
the host with the ability to detect and respond to infection by viruses and other …

[PDF][PDF] Cell culture media: a review

M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

Modulation of NF-κB signalling by microbial pathogens

MM Rahman, G McFadden - Nature Reviews Microbiology, 2011 - nature.com
The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …