We present the results for CAPRI Round 50, the fourth joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of twelve targets, including six dimers …

Prediction of the structure of protein complexes by docking methods is a well-established
research field. The intermolecular energy landscapes in protein–protein interactions can be …

We present the results for CAPRI Round 46, the third joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of 20 targets including 14 homo …

Antibodies recognize their cognate antigens with high affinity and specificity, but the
prediction of binding sites on the antigen (epitope) corresponding to a specific antibody …

Motivation The scoring of antibody–antigen docked poses starting from unbound homology
models has not been systematically optimized for a large and diverse set of input …

Protein docking is essential for structural characterization of protein interactions. Besides
providing the structure of protein complexes, modeling of proteins and their complexes is …

Microbes, commensals, and pathogens, control the numerous functions in the host cells.
They can alter host signaling and modulate immune surveillance by interacting with the host …

Highlights•Structural modeling of a cell is an evolving strategic direction.•Experimental
techniques provide data and validation for the modeling.•Key modeling approaches to …

The template-based approach has been essential for achieving high-quality models in the
recent rounds of blind protein-protein docking competition CAPRI (Critical Assessment of …

Motivation Template-based and template-free methods have both been widely used in
predicting the structures of protein–protein complexes. Template-based modeling is effective …