Aromatase in the brain of teleost fish: expression, regulation and putative functions
Unlike that of mammals, the brain of teleost fish exhibits an intense aromatase activity due to
the strong expression of one of two aromatase genes (aromatase A or cyp19a1a and …
the strong expression of one of two aromatase genes (aromatase A or cyp19a1a and …
Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides
Neuroactive steroids synthesized in neuronal tissue, referred to as neurosteroids, are
implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids …
implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids …
Neuron-derived estrogen is critical for astrocyte activation and neuroprotection of the ischemic brain
17β-Estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2
is known to be made in neurons in the brain, but the functions of neuron-derived E2 in the …
is known to be made in neurons in the brain, but the functions of neuron-derived E2 in the …
Forebrain steroid levels fluctuate rapidly during social interactions
Neurosteroids are powerful modulators of brain function and behavior, yet their dynamics in
the brain have remained elusive. Using in vivo microdialysis in male zebra finches, we found …
the brain have remained elusive. Using in vivo microdialysis in male zebra finches, we found …
Aromatase in the brain: not just for reproduction anymore
Aromatase, the enzyme that synthesises oestrogens from androgen precursors, is
expressed in the brain, where it has been classically associated with the regulation of …
expressed in the brain, where it has been classically associated with the regulation of …
Brain estrogens rapidly strengthen auditory encoding and guide song preference in a songbird
Higher cognitive function depends on accurate detection and processing of subtle features
of sensory stimuli. Such precise computations require neural circuits to be modulated over …
of sensory stimuli. Such precise computations require neural circuits to be modulated over …
Functional significance of the rapid regulation of brain estrogen action: where do the estrogens come from?
Estrogens exert a wide variety of actions on reproductive and non-reproductive functions.
These effects are mediated by slow and long lasting genomic as well as rapid and transient …
These effects are mediated by slow and long lasting genomic as well as rapid and transient …
Insights into rapid modulation of neuroplasticity by brain estrogens
Converging evidence from cellular, electrophysiological, anatomic, and behavioral studies
suggests that the remodeling of synapse structure and function is a critical component of …
suggests that the remodeling of synapse structure and function is a critical component of …
Synaptocrine signaling: steroid synthesis and action at the synapse
Sex steroids have long been recognized for their dramatic impact on brain and behavior,
including rapid modulation of membrane excitability. It is a widely held perception that these …
including rapid modulation of membrane excitability. It is a widely held perception that these …
Neuroendocrinology of song behavior and avian brain plasticity: multiple sites of action of sex steroid hormones
Seasonal changes in the brain of songbirds are one of the most dramatic examples of
naturally occuring neuroplasticity that have been described in any vertebrate species. In …
naturally occuring neuroplasticity that have been described in any vertebrate species. In …