Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Neuromodulation in epilepsy: state-of-the-art approved therapies

P Ryvlin, S Rheims, LJ Hirsch, A Sokolov… - The Lancet …, 2021 - thelancet.com
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Epilepsy in adults

RD Thijs, R Surges, TJ O'Brien, JW Sander - The lancet, 2019 - thelancet.com
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Critical review of transcutaneous vagus nerve stimulation: challenges for translation to clinical practice

JYY Yap, C Keatch, E Lambert, W Woods… - Frontiers in …, 2020 - frontiersin.org
Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can
elicit therapeutic effects that are similar to those produced by its invasive counterpart, vagus …

[HTML][HTML] Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review

DH Toffa, L Touma, T El Meskine, A Bouthillier… - Seizure, 2020 - Elsevier
Three decades after its introduction as an adjuvant therapeutic option in the management of
selective drug-resistant epilepsy cases (DRE), vagus nerve stimulation (VNS) retains …

Automated seizure detection using wearable devices: a clinical practice guideline of the International League Against Epilepsy and the International Federation of …

S Beniczky, S Wiebe, J Jeppesen, WO Tatum… - Clinical …, 2021 - Elsevier
The objective of this clinical practice guideline (CPG) is to provide recommendations for
healthcare personnel working with patients with epilepsy, on the use of wearable devices for …

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Machine learning and wearable devices of the future

S Beniczky, P Karoly, E Nurse, P Ryvlin, M Cook - Epilepsia, 2021 - Wiley Online Library
Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Vagus nerve stimulation for the treatment of epilepsy

HFJ González, A Yengo-Kahn… - Neurosurgery …, 2019 - neurosurgery.theclinics.com
Approximately 50 million people worldwide suffer from epilepsy, and approximately 30% to
40% of these persons have seizures that are refractory to treatment with antiepileptic …

[HTML][HTML] Automated seizure detection systems and their effectiveness for each type of seizure

A Ulate-Campos, F Coughlin, M Gaínza-Lein… - Seizure, 2016 - Elsevier
Epilepsy affects almost 1% of the population and most of the approximately 20–30% of
patients with refractory epilepsy have one or more seizures per month. Seizure detection …