MR elastography of the brain and its application in neurological diseases

MC Murphy, J Huston III, RL Ehman - Neuroimage, 2019 - Elsevier
Magnetic resonance elastography (MRE) is an imaging technique for noninvasively and
quantitatively assessing tissue stiffness, akin to palpation. MRE is further able assess the …

A clinical primer for the glymphatic system

LP Carlstrom, A Eltanahy, A Perry, AA Rabinstein… - Brain, 2022 - academic.oup.com
The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …

Stiffness and beyond: what MR elastography can tell us about brain structure and function under physiologic and pathologic conditions

Z Yin, AJ Romano, A Manduca, RL Ehman… - Topics in Magnetic …, 2018 - journals.lww.com
Brain magnetic resonance elastography (MRE) was developed on the basis of a desire to
“palpate by imaging” and is becoming a powerful tool in the investigation of …

Feasibility of assessing non-invasive intracranial compliance using FSI simulation-based and MR elastography-based brain stiffness

S Gholampour - Scientific Reports, 2024 - nature.com
Intracranial compliance (ICC) refers to the change in intracranial volume per unit change in
intracranial pressure (ICP). Magnetic resonance elastography (MRE) quantifies brain …

Identification of normal pressure hydrocephalus by disease-specific patterns of brain stiffness and dam** ratio

MC Murphy, PM Cogswell, JD Trzasko… - Investigative …, 2020 - journals.lww.com
Objectives The aim of this study was to perform a whole-brain analysis of alterations in brain
mechanical properties due to normal pressure hydrocephalus (NPH). Materials and …

Harnessing brain waves: a review of brain magnetic resonance elastography for clinicians and scientists entering the field

A Arani, A Manduca, RL Ehman… - The British journal of …, 2021 - academic.oup.com
Brain magnetic resonance elastography (MRE) is an imaging technique capable of
accurately and non-invasively measuring the mechanical properties of the living human …

Prediction of surgical outcomes in normal pressure hydrocephalus by MR elastography

P Karki, MC Murphy, PM Cogswell… - American Journal …, 2024 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Normal pressure hydrocephalus is a treatable cause of
dementia associated with distinct mechanical property signatures in the brain as measured …

Magnetic resonance elastography of the ageing brain in normal and demented populations: A systematic review

A Coelho, N Sousa - Human Brain Map**, 2022 - Wiley Online Library
The aim of this systematic review was to evaluate the ability of magnetic resonance
elastography (MRE) to identify significant changes in brain mechanical properties during …

Poroelastic mechanical properties of the brain tissue of normal pressure hydrocephalus patients during lumbar drain treatment using intrinsic actuation MR …

LM Solamen, MDJ McGarry, J Fried, JB Weaver… - Academic radiology, 2021 - Elsevier
Rationale and Objectives Hydrocephalus (HC) is caused by accumulating cerebrospinal
fluid resulting in enlarged ventricles and neurological symptoms. HC can be treated via a …

In vivo time-harmonic ultrasound elastography of the human brain detects acute cerebral stiffness changes induced by intracranial pressure variations

H Tzschätzsch, B Kreft, F Schrank, J Bergs, J Braun… - Scientific reports, 2018 - nature.com
Cerebral stiffness (CS) reflects the biophysical environment in which neurons grow and
function. While long-term CS changes can occur in the course of chronic neurological …