Bacterial lipases

KE Jaeger, S Ransac, BW Dijkstra… - FEMS microbiology …, 1994 - academic.oup.com
Many different bacterial species produce lipases which hydrolyze esters of glycerol with
preferably long-chain fatty acids. They act at the interface generated by a hydrophobic lipid …

Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases

KE Jaeger, BW Dijkstra, MT Reetz - Annual Reviews in …, 1999 - annualreviews.org
▪ Abstract Bacteria produce and secrete lipases, which can catalyze both the hydrolysis and
the synthesis of long-chain acylglycerols. These reactions usually proceed with high …

Lipase protein engineering

A Svendsen - Biochimica et Biophysica Acta (BBA)-Protein Structure …, 2000 - Elsevier
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Advances in recombinant lipases: Production, engineering, immobilization and application in the pharmaceutical industry

FJ Contesini, MG Davanço, GP Borin, KG Vanegas… - Catalysts, 2020 - mdpi.com
Lipases are one of the most used enzymes in the pharmaceutical industry due to their
efficiency in organic syntheses, mainly in the production of enantiopure drugs. From an …

Purification and preliminary characterization of the extracellular lipase of Bacillus subtilis 168, an extremely basic pH‐tolerant enzyme

E Lesuisse, K Schanck, C Colson - European Journal of …, 1993 - Wiley Online Library
The extracellular lipase of Bacillus subtilis 168 was purified from the growth medium of an
overproducing strain by ammonium sulfate precipitation followed by phenyl‐Sepharose and …

Compilation and analysus of Bacillus Subtilis σ A -dependent promoter sequences: evidence for extended contact between RNA …

JD Helmann - Nucleic acids research, 1995 - academic.oup.com
Sequence analysis of 236 promoters recognized by the Bacillus subtilis σARNA polymerase
reveals an extended promoter structure. The most highly conserved bases include the− 35 …

The crystal structure of Bacillus subtili lipase: a minimal α/β hydrolase fold enzyme

G Van Pouderoyen, T Eggert, KE Jaeger… - Journal of molecular …, 2001 - Elsevier
The X-ray structure of the lipase LipA from Bacillus subtilis has been determined at 1.5 Å
resolution. It is the first structure of a member of homology family I. 4 of bacterial lipases. The …

Thermoalkalophilic lipase of Bacillus thermocatenulatus. I. Molecular cloning, nucleotide sequence, purification and some properties

C Schmidt-Dannert, ML Rua, H Atomi… - Biochimica et Biophysica …, 1996 - Elsevier
An expression library was generated by partial Sau3A digestion of genomic DNA from the
thermophile Bacillus thermocatenulatus and cloning of DNA fragments in pUC18 in …

Screening, purification and properties of a thermophilic lipase from Bacillus thermocatenulatus

C Schmidt-Dannert, H Sztajer, W Stöcklein… - … et Biophysica Acta (BBA …, 1994 - Elsevier
By screening of 15 thermophilic Bacillus strains, five strains exhibiting lipase activity were
found. Among these the strain Bacillus thermocatenulatus (DSM 730) produced the highest …

Gene Cloning and Characterization of Thermostable Lipase from Bacillus stearothermophilus L1

HK Kim, SY Park, JK Lee, TK Oh - Bioscience, biotechnology, and …, 1998 - Taylor & Francis
The gene coding for an extracellular lipase of Bacillus stearothermophilus L1 was cloned in
Escherichia coli. Sequence analysis showed an open reading frame of 1254 bp, which …