Physiology and pathophysiology of human airway mucus

DB Hill, B Button, M Rubinstein… - Physiological …, 2022 - journals.physiology.org
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

[HTML][HTML] British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD)

CS Haworth, J Banks, T Capstick, AJ Fisher, T Gorsuch… - Thorax, 2017 - thorax.bmj.com
Background Since the publication of the British Thoracic Society (BTS) Guideline on the
'Management of opportunistic mycobacterial infections' in 2000, our understanding of the …

Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)

JD Chalmers, E Polverino, ML Crichton… - The Lancet …, 2023 - thelancet.com
Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …

The rise of non-tuberculosis mycobacterial lung disease

CN Ratnatunga, VP Lutzky, A Kupz, DL Doolan… - Frontiers in …, 2020 - frontiersin.org
The incidence and number of deaths from non-tuberculous mycobacterial (NTM) disease
have been steadily increasing globally. These lesser known “cousins” of Mycobacterium …

Advances in bronchiectasis: endoty**, genetics, microbiome, and disease heterogeneity

PA Flume, JD Chalmers, KN Olivier - The Lancet, 2018 - thelancet.com
Bronchiectasis is characterised by pathological dilation of the airways. More specifically, the
radiographic demonstration of airway enlargement is the common feature of a …

Cutaneous mycobacterial infections

C Franco-Paredes, LA Marcos… - Clinical microbiology …, 2018 - Am Soc Microbiol
Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …

[HTML][HTML] Update on pulmonary disease due to non-tuberculous mycobacteria

JE Stout, WJ Koh, WW Yew - International Journal of Infectious Diseases, 2016 - Elsevier
Non-tuberculous mycobacteria (NTM) are emerging worldwide as significant causes of
chronic pulmonary infection, posing a number of challenges for both clinicians and …

Host susceptibility to non-tuberculous mycobacterial infections

UI Wu, SM Holland - The Lancet infectious diseases, 2015 - thelancet.com
Non-tuberculous mycobacteria cause a broad range of clinical disorders, from cutaneous
infections, such as cervical or intrathoracic lymphadenitis in children, to disseminated …

Nontuberculous mycobacteria—overview

WJ Koh - Microbiology spectrum, 2017 - Am Soc Microbiol
Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both
immunocompromised and immunocompetent patients. The development of molecular …

The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases

SL Baldwin, SE Larsen, D Ordway… - PLoS neglected …, 2019 - journals.plos.org
Seemingly innocuous nontuberculous mycobacteria (NTM) species, classified by their slow
or rapid growth rates, can cause a wide range of illnesses, from skin ulceration to severe …