The development of efficient and environmentally benign synthetic protocols has attracted
increasing interest in modern organic syntheses in view of the growing concern over the …

Biginelli reaction involves acid-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1 H)-
ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active …

Optically pure nitrogenous compounds, and especially nitrogen-containing heterocycles,
have drawn intense research attention because of their frequent isolation as natural …

Metal organic frameworks (MOFs) are porous crystalline solids whose structure is formed by
metal ions or clusters of a few metal ions held in place by bi-or multipodal organic linkers. In …

The exploration of privileged structures in drug discovery is a rapidly emerging theme in
medicinal chemistry. These structures represent a class of molecules capable of binding to …

Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …

Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which,
in recent decades, have aroused interest in medicinal chemistry due to alleged versatile …

Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Multicomponent reactions are flexible reactions for the rapid generation of complex
molecules with often biologically relevant scaffold structures. Combined with the ease of …

Tailored to the needs of medicinal and natural products chemists, the second edition of this
unique handbook brings the contents up to speed, almost doubling the amount of chemical …