Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal
cord is limited by low specificity regarding the underlying pathological processes, and new …

Although iron is crucial for neuronal functioning, many aspects of cerebral iron biology await
clarification. The ability to quantify specific iron forms in the living brain would open new …

The neocortex of the human brain is the seat of higher brain function. Modern imaging
techniques, chief among them magnetic resonance imaging (MRI), allow non-invasive …

Purpose A method named DECOMPOSE-QSM is developed to decompose bulk
susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Diffusion-weighted MRI is our most promising method for estimating microscopic tissue
morphology in vivo. The signal acquisition is based on scanner-generated ex ternal …

With myelin playing a vital role in normal brain integrity and function and thus in various
neurological disorders, myelin sensitive magnetic resonance imaging (MRI) techniques are …

Post-mortem magnetic resonance imaging (MRI) provides the opportunity to acquire high-
resolution datasets to investigate neuroanatomy and validate the origins of image contrast …