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Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
Clinical intervention using focused ultrasound (FUS) stimulation of the brain in diverse neurological disorders
Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …
The relevance of skull density ratio in selecting candidates for transcranial MR-guided focused ultrasound
OBJECTIVE Transcranial MR-guided focused ultrasound (MRgFUS) is a minimally invasive
treatment for movement disorders. Considerable interpatient variability in skull transmission …
treatment for movement disorders. Considerable interpatient variability in skull transmission …
Impact of skull density ratio on efficacy and safety of magnetic resonance–guided focused ultrasound treatment of essential tremor
OBJECTIVE Skull density ratio (SDR) assesses the transparency of the skull to ultrasound.
Magnetic resonance–guided focused ultrasound (MRgFUS) thalamotomy in essential tremor …
Magnetic resonance–guided focused ultrasound (MRgFUS) thalamotomy in essential tremor …
Evaluating the safety profile of focused ultrasound and microbubble-mediated treatments to increase blood-brain barrier permeability
Introduction: Treatment of several diseases of the brain are complicated by the presence of
the skull and the blood-brain barrier (BBB). Focused ultrasound (FUS) and microbubble …
the skull and the blood-brain barrier (BBB). Focused ultrasound (FUS) and microbubble …
Ultrafast three-dimensional microbubble imaging in vivo predicts tissue damage volume distributions during nonthermal brain ablation
Transcranial magnetic resonance imaging (MRI)-guided focused ultrasound (FUS) thermal
ablation is under clinical investigation for non-invasive neurosurgery, though its use is …
ablation is under clinical investigation for non-invasive neurosurgery, though its use is …
Two-step aberration correction: application to transcranial histotripsy
N Lu, TL Hall, JR Sukovich, SW Choi… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective: Phase aberration correction is essential in transcranial histotripsy to compensate
for focal distortion caused by the heterogeneity of the intact skull bone. This paper improves …
for focal distortion caused by the heterogeneity of the intact skull bone. This paper improves …
Molecular Modeling of Shockwave-Mediated Blood-Brain Barrier Opening for Targeted Drug Delivery
M Zhou, W Zhou, H Yang, L Cao, M Li… - … Applied Materials & …, 2024 - ACS Publications
Bubble-enhanced shock waves induce the transient opening of the blood-brain barrier
(BBB) providing unique advantages for targeted drug delivery of brain tumor therapy, but …
(BBB) providing unique advantages for targeted drug delivery of brain tumor therapy, but …
Accumulated thermal dose in MRI-guided focused ultrasound for essential tremor: repeated sonications with low focal temperatures
RM Jones, S Kamps, Y Huang, N Scantlebury… - Journal of …, 2019 - thejns.org
OBJECTIVE The object of this study was to correlate lesion size with accumulated thermal
dose (ATD) in transcranial MRI-guided focused ultrasound (MRgFUS) treatments of …
dose (ATD) in transcranial MRI-guided focused ultrasound (MRgFUS) treatments of …
Echo‐focusing in transcranial focused ultrasound thalamotomy for essential tremor: A feasibility study
RM Jones, Y Huang, Y Meng, N Scantlebury… - Movement …, 2020 - Wiley Online Library
Background Transcranial magnetic resonance–guided focused ultrasound (TcMRgFUS)
systems currently employ computed tomography (CT)–based aberration corrections, which …
systems currently employ computed tomography (CT)–based aberration corrections, which …