Zebrafish embryos and larvae: a new generation of disease models and drug screens

S Ali, DL Champagne, HP Spaink… - … Research Part C …, 2011 - Wiley Online Library
Technological innovation has helped the zebrafish embryo gain ground as a disease model
and an assay system for drug screening. Here, we review the use of zebrafish embryos and …

A new wave of cellular imaging

D Toomre, J Bewersdorf - Annual review of cell and …, 2010 - annualreviews.org
Fluorescence imaging methods that push or break the diffraction limit of resolution
(approximately 200 nm) have grown explosively. These super-resolution nanoscopy …

Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging

DM Shcherbakova, M Baloban, AV Emelyanov… - Nature …, 2016 - nature.com
Monomeric near-infrared (NIR) fluorescent proteins (FPs) are in high demand as protein
tags and components of biosensors for deep-tissue imaging and multicolour microscopy. We …

Near-infrared fluorescent proteins for multicolor in vivo imaging

DM Shcherbakova, VV Verkhusha - Nature methods, 2013 - nature.com
Near-infrared fluorescent proteins (FPs) are in high demand for in vivo imaging. We
developed four spectrally distinct near-infrared FPs—iRFP670, iRFP682, iRFP702 and …

Bright and stable near-infrared fluorescent protein for in vivo imaging

GS Filonov, KD Piatkevich, LM Ting, J Zhang… - Nature …, 2011 - nature.com
Imaging biological processes in mammalian tissues will be facilitated by fluorescent probes
with excitation and emission bands within the near-infrared optical window of high …

[BOK][B] FRET-Förster resonance energy transfer: from theory to applications

IL Medintz, N Hildebrandt - 2013 - books.google.com
FRET–Förster Resonance Energy Transfer Meeting the need for an up-to-date and detailed
primer on all aspects of the topic, this ready reference reflects the incredible expansion in …

A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales

ME Matlashov, DM Shcherbakova, J Alvelid… - Nature …, 2020 - nature.com
Bright monomeric near-infrared (NIR) fluorescent proteins (FPs) are in high demand as
protein tags for multicolor microscopy and in vivo imaging. Here we apply rational design to …

Systematic methodological evaluation of a multiplex bead-based flow cytometry assay for detection of extracellular vesicle surface signatures

OPB Wiklander, RB Bostancioglu, JA Welsh… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs) can be harvested from cell culture supernatants and from all
body fluids. EVs can be conceptually classified based on their size and biogenesis as …

Intravital third harmonic generation microscopy of collective melanoma cell invasion: Principles of interface guidance and microvesicle dynamics

B Weigelin, GJ Bakker, P Friedl - IntraVital, 2012 - Taylor & Francis
Cancer cell invasion is an adaptive process based on cell-intrinsic properties to migrate
individually or collectively, and their adaptation to encountered tissue structure acting as …

Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection

D Adamoski, MM Dias, JEN Quesñay, Z Yang… - Nature structural & …, 2023 - nature.com
Glutaminase (GLS), which deaminates glutamine to form glutamate, is a mitochondrial
tetrameric protein complex. Although inorganic phosphate (Pi) is known to promote GLS …