[HTML][HTML] Engineering organoids as cerebral disease models

A Geidies, MLJ Medar, HM Beyer - Current Opinion in Biotechnology, 2025 - Elsevier
Highlights•Relevance of organoid cultures in cerebral disease modeling.•Review of
organoid and stem cell engineering principles.•Examples for engineered cerebral disease …

Patient-derived induced pluripotent stem cell organoids for amyotrophic lateral sclerosis drug discovery

W Li, J Liu, W Li, L Sun, H Zhang, L Gao… - Acta Materia …, 2025 - scienceopen.com
Complex biological mechanisms and unidentified therapeutic targets for amyotrophic lateral
sclerosis (ALS) significantly hinder the development of effective treatments. Given these …

Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …

L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

[PDF][PDF] Wissen, wo das Wissen ist.

A Geidies, MLJ Medar… - Current Opinion in …, 2025 - docserv.uni-duesseldorf.de
The complexity of the human brain represents a major challenge in our aims to disentangle
the structure and function of the organ and gather a growing understanding of neurological …