Spatiotemporal omics for biology and medicine
The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …
understanding human life. Nonetheless, understanding the intricate mechanisms through …
Community standards and future opportunities for synthetic communities in plant–microbiota research
Harnessing beneficial microorganisms is seen as a promising approach to enhance
sustainable agriculture production. Synthetic communities (SynComs) are increasingly …
sustainable agriculture production. Synthetic communities (SynComs) are increasingly …
LIANA+ provides an all-in-one framework for cell–cell communication inference
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …
development of many approaches to infer cell–cell communication, each capturing only a …
Spatial map** of mobile genetic elements and their bacterial hosts in complex microbiomes
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …
Unraveling plant–microbe symbioses using single-cell and spatial transcriptomics
Plant–microbe symbioses require intense interaction and genetic coordination to
successfully establish in specific cell types of the host and symbiont. Traditional RNA-seq …
successfully establish in specific cell types of the host and symbiont. Traditional RNA-seq …
Integrating single-cell multi-omics and prior biological knowledge for a functional characterization of the immune system
The immune system comprises diverse specialized cell types that cooperate to defend the
host against a wide range of pathogenic threats. Recent advancements in single-cell and …
host against a wide range of pathogenic threats. Recent advancements in single-cell and …
Challenges and Opportunities in the Clinical Translation of High-Resolution Spatial Transcriptomics
Pathology has always been fueled by technological advances. Histology powered the study
of tissue architecture at single-cell resolution and remains a cornerstone of clinical …
of tissue architecture at single-cell resolution and remains a cornerstone of clinical …
Comparative Cross-Kingdom DDA-and DIA-PASEF Proteomic Profiling Reveals Novel Determinants of Fungal Virulence and a Putative Druggable Target
B Ball, A Sukumaran, JR Krieger… - Journal of Proteome …, 2024 - ACS Publications
Accurate and reliable detection of fungal pathogens presents an important hurdle to manage
infections, especially considering that fungal pathogens, including the globally important …
infections, especially considering that fungal pathogens, including the globally important …
Advancing our understanding of root development: Technologies and insights from diverse studies
Understanding root development is critical for enhancing plant growth and health, and
advanced technologies are essential for unraveling the complexities of these processes. In …
advanced technologies are essential for unraveling the complexities of these processes. In …
Next-Generation Sequencing-Based Spatial Transcriptomics: A Perspective from Barcoding Chemistry
Gene expression profiling of tissue cells with spatial context is in high demand to reveal cell
types, locations, and intercellular or molecular interactions for physiological and …
types, locations, and intercellular or molecular interactions for physiological and …