The role of miRNAs in liver diseases: Potential therapeutic and clinical applications

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

Diagnosis and therapeutic management of liver fibrosis by MicroRNA

T Tadokoro, A Morishita, T Masaki - International Journal of Molecular …, 2021 - mdpi.com
Remarkable progress has been made in the treatment and control of hepatitis B and C viral
infections. However, fundamental treatments for diseases in which liver fibrosis is a key …

Serum biomarkers for the prediction of hepatocellular carcinoma

JD Debes, PA Romagnoli, J Prieto, M Arrese… - Cancers, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is a leading cause of global cancer death. Major etiologies
of HCC relate to chronic viral infections as well as metabolic conditions. The survival rate of …

[HTML][HTML] microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer

S Nagaraj, KM Zoltowska, K Laskowska-Kaszub… - Ageing research …, 2019 - Elsevier
Abstract microRNAs (miRNAs) have been extensively studied as potential biomarkers for
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …

AS1411 aptamer-decorated cisplatin-loaded poly(lactic-co-glycolic acid) Nanoparticles for Targeted Therapy of miR-21-inhibited Ovarian Cancer Cells

S Vandghanooni, M Eskandani, J Barar, Y Omidi - Nanomedicine, 2018 - Taylor & Francis
Aim: The overexpression of miRNA-21 correlates with the cisplatin (CIS) resistance in the
ovarian cancers. Methods: AS1411 antinucleolin aptamer-decorated PEGylated poly (lactic …

miRNAs as potential biomarkers for viral hepatitis B and C

D Loureiro, I Tout, S Narguet, SM Benazzouz… - Viruses, 2020 - mdpi.com
Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71
million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead …

The role of miR‐146a in viral infection

JS Nahand, MR Karimzadeh, M Nezamnia… - IUBMB …, 2020 - Wiley Online Library
Cellular microRNAs (miRNAs) were identified as a key player in the posttranscriptional
regulation of cellular‐genes regulatory pathways. They also emerged as a significant …

[HTML][HTML] Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids

W Okajima, S Komatsu, D Ichikawa… - World Journal of …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), with its high incidence and mortality rate, is one of the
most common malignant tumors. Despite recent development of a diagnostic and treatment …

Circulating microRNAs as potential biomarkers in non-alcoholic fatty liver disease and hepatocellular carcinoma

MB Afonso, PM Rodrigues, AL Simao… - Journal of clinical …, 2016 - mdpi.com
Obesity and metabolic syndrome are growing epidemics worldwide and greatly responsible
for many liver diseases, including nonalcoholic fatty liver disease (NAFLD). NAFLD often …

Biomarker MicroRNAs for diagnosis, prognosis and treatment of hepatocellular carcinoma: a functional survey and comparison

S Shen, Y Lin, X Yuan, L Shen, J Chen, L Chen… - Scientific reports, 2016 - nature.com
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumors with high
incidence and mortality rate. Precision and effective biomarkers are therefore urgently …