The fourth edition of the World Health Organization (WHO) classification of tumours of the
central nervous system, published in 2007, lists several new entities, including angiocentric …

Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …

The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of
adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas …

Purpose To provide guidance to clinicians regarding therapy for diffuse astrocytic and
oligodendroglial tumors in adults. Methods ASCO and the Society for Neuro-Oncology …

This guideline provides recommendations for diagnostic and therapeutic procedures for
patients with malignant gliomas. We differentiate evidence-based standards from …

Abstract The Chinese Glioma Cooperative Group (CGCG) Guideline Panel for adult diffuse
gliomas provided recommendations for diagnostic and therapeutic procedures. The Panel …

Purpose Anaplastic oligodendrogliomas, pure (AO) and mixed (anaplastic oligoastrocytoma
[AOA]), are chemosensitive, especially if codeleted for 1p/19q, but whether patients live …

Important advances have been made in the understanding and management of adult
gliomas and primary CNS lymphomas—the two most common primary brain tumours …

Diffuse gliomas are up till now graded based upon morphology. Recent findings indicate
that isocitrate dehydrogenase (IDH) mutation status defines biologically distinct groups of …

The DNA repair enzyme O 6-methylguanine-DNA methyltransferase (MGMT) antagonizes
the genotoxic effects of alkylating agents. MGMT promoter methylation is the key mechanism …