Deep sequencing of somatosensory neurons reveals molecular determinants of intrinsic physiological properties

Y Zheng, P Liu, L Bai, JS Trimmer, BP Bean, DD Ginty - Neuron, 2019 - cell.com
Dorsal root ganglion (DRG) sensory neuron subtypes defined by their in vivo properties
display distinct intrinsic electrical properties. We used bulk RNA sequencing of genetically …

Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes

D Anderson, WH Mehaffey, M Iftinca, R Rehak… - Nature …, 2010 - nature.com
Kv4 low voltage–activated A-type potassium channels are widely expressed in excitable
cells, where they control action potential firing, dendritic activity and synaptic integration. Kv4 …

Signaling complexes of voltage-gated calcium channels

RW Turner, D Anderson, GW Zamponi - Channels, 2011 - Taylor & Francis
Voltage gated calcium channels are key mediators of depolarization induced calcium entry
into electrically excitable cells. There is increasing evidence that voltage gated calcium …

CaV3 T‐type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons

BE McKay, JE McRory, ML Molineux… - European Journal of …, 2006 - Wiley Online Library
Spike output in many neuronal cell types is affected by low‐voltage‐activated T‐type
calcium currents arising from the Cav3. 1, Cav3. 2 and Cav3. 3 channel subtypes and their …

Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons

ML Molineux, JE McRory, BE McKay… - Proceedings of the …, 2006 - National Acad Sciences
T-type calcium channels are thought to transform neuronal output to a burst mode by
generating low voltage-activated (LVA) calcium currents and rebound burst discharge. In …

Sexually dimorphic neuronal responses to social isolation

L Senst, D Baimoukhametova, TL Sterley, JS Bains - elife, 2016 - elifesciences.org
Many species use social networks to buffer the effects of stress. The mere absence of a
social network, however, may also be stressful. We examined neuroendocrine, PVN CRH …

T-type channels buddy up

RW Turner, GW Zamponi - Pflügers Archiv-European Journal of Physiology, 2014 - Springer
The electrical output of neurons relies critically on voltage-and calcium-gated ion channels.
The traditional view of ion channels is that they operate independently of each other in the …

[HTML][HTML] Thin dendrites of cerebellar interneurons confer sublinear synaptic integration and a gradient of short-term plasticity

T Abrahamsson, L Cathala, K Matsui, R Shigemoto… - Neuron, 2012 - cell.com
Interneurons are critical for neuronal circuit function, but how their dendritic morphologies
and membrane properties influence information flow within neuronal circuits is largely …

Lhx3-Chx10 reticulospinal neurons in locomotor circuits

F Bretzner, RM Brownstone - Journal of Neuroscience, 2013 - Soc Neuroscience
Motor behaviors result from the interplay between the brain and the spinal cord.
Reticulospinal neurons, situated between the supraspinal structures that initiate motor …

Diverse neuron properties and complex network dynamics in the cerebellar cortical inhibitory circuit

F Prestori, L Mapelli, E D'Angelo - Frontiers in molecular neuroscience, 2019 - frontiersin.org
Neuronal inhibition can be defined as a spatiotemporal restriction or suppression of local
microcircuit activity. The importance of inhibition relies in its fundamental role in sha** …