Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms
Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …
both hospital and community settings, especially with the widespread emergence of virulent …
Vaccination against bacterial infections: challenges, progress, and new approaches with a focus on intracellular bacteria
A Osterloh - Vaccines, 2022 - mdpi.com
Many bacterial infections are major health problems worldwide, and treatment of many of
these infectious diseases is becoming increasingly difficult due to the development of …
these infectious diseases is becoming increasingly difficult due to the development of …
The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development
A Bear, T Locke, S Rowland-Jones… - Frontiers in Cellular …, 2023 - frontiersin.org
While Staphylococcus aureus (S. aureus) bacteria are part of the human commensal flora,
opportunistic invasion following breach of the epithelial layers can lead to a wide array of …
opportunistic invasion following breach of the epithelial layers can lead to a wide array of …
[HTML][HTML] Anti-virulence compounds against Staphylococcus aureus associated with bovine mastitis: A new therapeutic option?
YNV Sabino, PD Cotter, HC Mantovani - Microbiological Research, 2023 - Elsevier
Bovine mastitis represents a major economic burden faced by the dairy industry. S. aureus is
an important and prevalent bovine mastitis-associated pathogen in dairy farms worldwide …
an important and prevalent bovine mastitis-associated pathogen in dairy farms worldwide …
Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?
Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …
IBT-V02: A Multicomponent Toxoid Vaccine Protects Against Primary and Secondary Skin Infections Caused by Staphylococcus aureus
Staphylococcus aureus causes a wide range of diseases from skin infections to life
threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site …
threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site …
rAAV expressing recombinant neutralizing antibody for the botulinum neurotoxin type a prophylaxis
AA Derkaev, EI Ryabova, IB Esmagambetov… - Frontiers in …, 2022 - frontiersin.org
Botulinum neurotoxin (BoNT) is one of the most dangerous bacterial toxins and a potential
biological weapon component. BoNT mechanism of pathological action is based on …
biological weapon component. BoNT mechanism of pathological action is based on …
Evasion of Immunological Memory by S. aureus Infection: Implications for Vaccine Design
Recurrent S. aureus infections are common, suggesting that natural immune responses are
not protective. All candidate vaccines tested thus far have failed to protect against S. aureus …
not protective. All candidate vaccines tested thus far have failed to protect against S. aureus …
Recent advances in genomics-based approaches for the development of intracellular bacterial pathogen vaccines
Infectious diseases continue to be a leading cause of morbidity and mortality worldwide. The
majority of infectious diseases are caused by intracellular pathogenic bacteria (IPB) …
majority of infectious diseases are caused by intracellular pathogenic bacteria (IPB) …
Dry and liquid formulations of IBT-V02, a novel multi-component toxoid vaccine, are effective against Staphylococcus aureus isolates from low-to-middle income …
Y Wang, I Mukherjee, A Venkatasubramaniam… - Frontiers in …, 2024 - frontiersin.org
Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs) in the
US as well as more serious invasive diseases, including bacteremia, sepsis, endocarditis …
US as well as more serious invasive diseases, including bacteremia, sepsis, endocarditis …