Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
Cyclodextrins as chiral selectors in capillary electrophoresis: Recent trends in mechanistic studies
B Chankvetadze, GKE Scriba - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In the present review the potential of capillary electrophoresis for a better understanding of
the fine structural mechanisms of noncovalent interactions and enantioselective …
the fine structural mechanisms of noncovalent interactions and enantioselective …
Chiral recognition in separation sciences. Part I: Polysaccharide and cyclodextrin selectors
GKE Scriba - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
The stereoselective recognition of chiral molecules is an important aspect in nature as the
basis of the interaction of chiral bioactive compounds with their target structures. In …
basis of the interaction of chiral bioactive compounds with their target structures. In …
Native and substituted cyclodextrins as chiral selectors for capillary electrophoresis enantioseparations: Structures, features, application, and molecular modeling
CDs are cyclic oligosaccharides consisting of α‐d‐glucopyranosyl units linked through 1, 4‐
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …
[HTML][HTML] Recent developments in molecular modeling tools and applications related to pharmaceutical and biomedical research
In modern pharmaceutical and biomedical research, molecular modeling represents a
useful tool to explore processes and their mechanistic bases at the molecular level …
useful tool to explore processes and their mechanistic bases at the molecular level …
Advances of capillary electrophoresis enantioseparations in pharmaceutical analysis (2017–2020)
S Krait, ML Konjaria, GKE Scriba - Electrophoresis, 2021 - Wiley Online Library
Capillary electrophoresis is a powerful technique for the analysis of polar chiral compounds
and has been widely accepted for analytical enantioseparations of drug compounds in …
and has been widely accepted for analytical enantioseparations of drug compounds in …
[HTML][HTML] Isothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by γ-cyclodextrin and trimethyl-β-cyclodextrin
The complex formation between daclatasvir and γ-CD or heptakis (2, 3, 6-tri-O-methyl)-β-CD
(TM-β-CD) was studied by isothermal titration calorimetry and molecular modeling. Both …
(TM-β-CD) was studied by isothermal titration calorimetry and molecular modeling. Both …
Noncovalent interactions in high-performance liquid chromatography enantioseparations on polysaccharide-based chiral selectors
Designed more than thirty years ago in order to improve and maximize the discrimination
capability of native polysaccharides, cellulose-and amylose-based selectors have shown …
capability of native polysaccharides, cellulose-and amylose-based selectors have shown …
Modelling approaches for chiral chromatography on polysaccharide-based and macrocyclic antibiotic chiral selectors: A review
P De Gauquier, K Vanommeslaeghe… - Analytica Chimica …, 2022 - Elsevier
An overview of molecular modelling approaches, related to chiral separations on
polysaccharide-based and macrocyclic antibiotic chiral selectors, is presented. Both …
polysaccharide-based and macrocyclic antibiotic chiral selectors, is presented. Both …
Molecular dynamics simulations of amylose-and cellulose-based selectors and related enantioseparations in liquid phase chromatography
In the last few decades, theoretical and technical advancements in computer facilities and
computational techniques have made molecular modeling a useful tool in liquid-phase …
computational techniques have made molecular modeling a useful tool in liquid-phase …