Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Uterine fibroids

EA Stewart, SK Laughlin-Tommaso… - Nature reviews Disease …, 2016 - nature.com
Uterine fibroids (also known as leiomyomas or myomas) are common clonal neoplasms of
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …

Epidemiology of uterine myomas: a review

R Sparic, L Mirkovic, A Malvasi… - International journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Myomas are the most common benign tumors of the genital organs in women of
childbearing age, causing significant morbidity and impairing their quality of life. In our …

Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics

MS Islam, A Ciavattini, F Petraglia… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

Uterine fibroids: hiding in plain sight

EA Stewart, RA Nowak - Physiology, 2022 - journals.physiology.org
Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …

Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth

AE Commandeur, AK Styer… - Human Reproduction …, 2015 - academic.oup.com
BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle
tumors of the uterus. In the USA, the lifetime risk for women develo** uterine leiomyomas …

Vitamin D and the risk of uterine fibroids

DD Baird, MC Hill, JM Schectman, BW Hollis - Epidemiology, 2013 - journals.lww.com
Background: Uterine leiomyomata (also known as fibroids) are benign tumors of uterine
smooth muscle that are characterized by overproduction of extracellular matrix. Fibroids are …

Uterine fibroids and diet

A Tinelli, M Vinciguerra, A Malvasi, M Andjić… - International journal of …, 2021 - mdpi.com
Uterine myomas or fibroids are the most common benign female tumors of the reproductive
organs, associated with significant morbidity and quality of life impairment. Several …

Uterine leiomyoma: available medical treatments and new possible therapeutic options

MS Islam, O Protic, SR Giannubilo, P Toti… - The Journal of …, 2013 - academic.oup.com
Context: Uterine leiomyomas (fibroids or myomas) are benign tumors of the uterus and are
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …

[HTML][HTML] Complex networks of multiple factors in the pathogenesis of uterine leiomyoma

MS Islam, O Protic, P Stortoni, G Grechi, P Lamanna… - Fertility and sterility, 2013 - Elsevier
OBJECTIVE: To summarize the information regarding pathogenetic factors of leiomyoma
formation and growth, and to make a simple integrated pathogenetic view of this tumor for …