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Illuminating the landscape of host–pathogen interactions with the bacterium Listeria monocytogenes
P Cossart - Proceedings of the National Academy of Sciences, 2011 - pnas.org
Listeria monocytogenes has, in 25 y, become a model in infection biology. Through the
analysis of both its saprophytic life and infectious process, new concepts in microbiology …
analysis of both its saprophytic life and infectious process, new concepts in microbiology …
Metabolic host responses to infection by intracellular bacterial pathogens
The interaction of bacterial pathogens with mammalian hosts leads to a variety of
physiological responses of the interacting partners aimed at an adaptation to the new …
physiological responses of the interacting partners aimed at an adaptation to the new …
Tyrosine phosphorylation and bacterial virulence
SE Whitmore, RJ Lamont - International journal of oral science, 2012 - nature.com
Protein phosphorylation on tyrosine has emerged as a key device in the control of numerous
cellular functions in bacteria. In this article, we review the structure and function of bacterial …
cellular functions in bacteria. In this article, we review the structure and function of bacterial …
Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development
Mycobacterium tuberculosis (Mtb) infects human alveolar macrophages and relies on the
inhibition of phagosome acidification and maturation. This is, in part, dependent on the …
inhibition of phagosome acidification and maturation. This is, in part, dependent on the …
Function of macrophage and parasite phosphatases in leishmaniasis
The kinetoplastid protozoan parasites belonging to the genus Leishmania are the causative
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …
Protein phosphatases of pathogenic bacteria: role in physiology and virulence
The role of protein phosphatases in pathogenic bacteria has been studied extensively over
the last two decades. Ser/Thr and Tyr phosphatases are associated with growth and …
the last two decades. Ser/Thr and Tyr phosphatases are associated with growth and …
Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo
CF Vickers, APG Silva, A Chakraborty… - Journal of medicinal …, 2018 - ACS Publications
Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence
factor that subverts antimicrobial activity in the host. We report here the structure-based …
factor that subverts antimicrobial activity in the host. We report here the structure-based …
Microbial community function in the bleaching disease of the marine macroalgae Delisea pulchra
Disease is increasingly viewed as a major factor impacting the health of both natural and
cultured populations of marine organisms, including macroalgae. The red macroalga …
cultured populations of marine organisms, including macroalgae. The red macroalga …
Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence
Phosphorylation is the most common and widely studied post‐translational protein
modification in bacteria. It plays an important role in all kinds of cellular processes and …
modification in bacteria. It plays an important role in all kinds of cellular processes and …
CD83 orchestrates immunity toward self and non-self in dendritic cells
AB Wild, L Krzyzak, K Peckert, L Stich, C Kuhnt… - JCI …, 2019 - pmc.ncbi.nlm.nih.gov
Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune
inflammatory processes. Expression of CD83 is a well-established marker for mature DCs …
inflammatory processes. Expression of CD83 is a well-established marker for mature DCs …