Hepatocellular carcinoma is the most common primary liver cancer, ranking third among the
leading causes of cancer-related mortality worldwide and whose incidence varies according …

Epigenetic and metabolic reprogramming alterations are two important features of tumors,
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …

Skeletal muscle is an important part of the human body. Most glucose metabolism is
accomplished by skeletal muscle through insulin mediation. Skeletal muscle metabolism …

DNA molecules in eukaryotes have long been thought to exist primarily in a linear form in
the nucleus [1]. However, in 1965, Hotta, et al.[2] found extrachromosomal circular DNA …

This abstract presents an overview of Trop2, a cell surface glycoprotein, and its significance
in cancer research. Trop2, also known as tumor-associated calcium signal transducer 2 …

Breast cancer is a heterogeneous disease characterized by distinct molecular and metabolic
characteristics, making its diagnostics and treatment challenging. The existence of metabolic …

Alzheimer's disease (AD) is a neurodegenerative condition that disrupts nerve cell function
due to the misfolding and buildup of proteins, resulting in cognitive loss and aberrant …

The stiffness of the tumor microenvironment (TME) is dynamic and drives metabolic
reprogramming in cancer cells as a consequence of tumor progression. To demonstrate the …

As a crucial protein kinase, the mammalian target of rapamycin (mTOR) intimately controls
essential cellular processes like cell development, proliferation, metabolism, and other …

Transposons are mobile DNA sequences abundant in eukaryotic genomes. Non-coding
small RNAs have various biological functions and affect gene expression at different levels …