Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Activity-based fluorescence diagnostics for cancer

K Fujita, Y Urano - Chemical reviews, 2024 - ACS Publications
Fluorescence imaging is one of the most promising approaches to achieve intraoperative
assessment of the tumor/normal tissue margins during cancer surgery. This is critical to …

Tumor-microenvironment-activatable organic phototheranostic agents for cancer therapy

S Zeng, Z Guo, Y Hao, YS Kafuti, Z Yang, Q Yao… - Coordination Chemistry …, 2024 - Elsevier
Tumor microenvironment is a rather unusual circumstances formed during the growth of
tumor cells, showing significant differences from normal cells and tissues. Indeed, many …

All-in-One Alkaline Phosphatase-Response Aggregation-Induced Emission Probe for Cancer Discriminative Imaging and Combinational Chemodynamic …

LH **ong, L Yang, J Geng, BZ Tang, X He - ACS nano, 2024 - ACS Publications
Currently, specific cancer-responsive fluorogenic probes with activatable imaging and
therapeutic functionalities are in great demand in the accurate diagnostics and efficient …

Dual-functional AIE fluorescent probe for visualization of lipid droplets and photodynamic therapy of cancer

S Pei, H Li, L Chen, G Nie, H Wang, C Liu… - Analytical …, 2024 - ACS Publications
Abnormal lipid droplets (LDs) are known to be intimately bound with the occurrence and
development of cancer, allowing LDs to be critical biomarkers for cancers. Aggregation …

PdCux Bimetallic Nanoalloys with “Hand‐in‐Hand” Collaboration in POD‐like Activity and “Back‐to‐Back” Confrontation in SPR Effect for Tumor Redox System …

L Fang, Y Zhang, H Ding, S Liu, J Wei… - Advanced Functional …, 2024 - Wiley Online Library
In reactive‐oxygen‐species‐mediated tumor therapy, the generation and accumulation of·
OH is highly dependent on peroxidase (POD)‐like enzymatic activities and the antioxidant …

Self-assembly strategies of organic small-molecule photosensitizers for photodynamic therapy

X **ong, J Liu, L Wu, S **ong, W Jiang… - Coordination Chemistry …, 2024 - Elsevier
In recent years, the use of organic small-molecule photosensitizers, which make up the
majority of photosensitizers, has significantly enhanced the therapeutic outcomes of various …

Mitochondria-targetable small molecule fluorescent probes for the detection of cancer-associated biomarkers: A review

X Yu, Y Huang, Y Tao, L Fan, Y Zhang - Analytica Chimica Acta, 2024 - Elsevier
Cancer represents a global threat to human health, and effective strategies for improved
cancer early diagnosis and treatment are urgently needed. The detection of tumor …

A POSS-based metal-phenolic network with coupled hardness and softness for photodynamic-immunotherapy of triple-negative breast cancer

W Wang, L Liao, Y Huang, Y Zhao, L Lei… - ACS Materials …, 2024 - ACS Publications
To overcome the oxidative stress and resistance of cancer stem cells (CSCs) for successful
metastatic triple-negative breast cancer (TNBC) treatment, we report polyhedral …

Aggregation-induced emission luminogen based ELISA for highly sensitive protein detection

C Chen, L Chen, Y Yang, R He, Y Deng, J Hu - Sensors and Actuators B …, 2024 - Elsevier
Enzyme-linked immunosorbent assay (ELISA), as the most commonly used immunological
detection technique, has been widely used in the clinical diagnosis of disease marker …