Cell-mediated immune responses in tuberculosis
AM Cooper - Annual review of immunology, 2009 - annualreviews.org
Tuberculosis is primarily a disease of the lung, and dissemination of the disease depends
on productive infection of this critical organ. Upon aerosol infection with Mycobacterium …
on productive infection of this critical organ. Upon aerosol infection with Mycobacterium …
Virulence factors of the Mycobacterium tuberculosis complex
MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
[HTML][HTML] Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
Background BCG vaccination provides incomplete protection against tuberculosis in infants.
A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was …
A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was …
Variable host–pathogen compatibility in Mycobacterium tuberculosis
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide.
Studies have reported human pathogens to have geographically structured population …
Studies have reported human pathogens to have geographically structured population …
The success and failure of BCG—implications for a novel tuberculosis vaccine
P Andersen, TM Doherty - Nature Reviews Microbiology, 2005 - nature.com
Over the past 50 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) vaccine
against tuberculosis (TB) has maintained its position as the world's most widely used …
against tuberculosis (TB) has maintained its position as the world's most widely used …
Modified vaccinia virus Ankara: history, value in basic research, and current perspectives for vaccine development
A Volz, G Sutter - Advances in virus research, 2017 - Elsevier
Abstract Safety tested Modified Vaccinia virus Ankara (MVA) is licensed as third-generation
vaccine against smallpox and serves as a potent vector system for development of new …
vaccine against smallpox and serves as a potent vector system for development of new …
Paediatric tuberculosis
SM Newton, AJ Brent, S Anderson… - The Lancet infectious …, 2008 - thelancet.com
Tuberculosis continues to cause an unacceptably high toll of disease and death among
children worldwide, particularly in the wake of the HIV epidemic. Increased international …
children worldwide, particularly in the wake of the HIV epidemic. Increased international …
[HTML][HTML] Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans
Background Adenovirus-vectored (Ad-vectored) vaccines are typically administered via im
injection to humans and are incapable of inducing respiratory mucosal immunity. However …
injection to humans and are incapable of inducing respiratory mucosal immunity. However …
Vaccines against tuberculosis: where are we and where do we need to go?
In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …
Therapeutic vaccines for tuberculosis: an overview
Tuberculosis (TB), caused by Mycobacterium tuberculosis is the world's deadliest bacterial
infection, resulting in more than 1.4 million deaths annually. The emergence of drug …
infection, resulting in more than 1.4 million deaths annually. The emergence of drug …