Penicillin allergy delabeling: a multidisciplinary opportunity

ML Staicu, D Vyles, ES Shenoy, CA Stone… - The Journal of Allergy …, 2020 - Elsevier
The penicillin allergy label has been consistently linked with deleterious effects that span the
health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial …

Hidden dangers: recognizing excipients as potential causes of drug and vaccine hypersensitivity reactions

ML Caballero, MS Krantz, S Quirce, EJ Phillips… - The Journal of Allergy …, 2021 - Elsevier
Excipients are necessary as a support to the active ingredients in drugs, vaccines, and other
products, and they contribute to their stability, preservation, pharmacokinetics …

[PDF][PDF] Drug allergy: a 2022 practice parameter update

DA Khan, A Banerji, KG Blumenthal, EJ Phillips… - Journal of Allergy and …, 2022 - Elsevier
Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial

AM Copaescu, S Vogrin, F James… - JAMA internal …, 2023 - jamanetwork.com
Importance Fewer than 5% of patients labeled with a penicillin allergy are truly allergic. The
standard of care to remove the penicillin allergy label in adults is specialized testing …

EAACI/ENDA position paper on drug provocation testing

A Barbaud, LH Garvey, M Torres, JJ Laguna… - Allergy, 2024 - Wiley Online Library
In drug hypersensitivity, drug provocation testing (DPT), also called drug challenge, is the
gold standard for investigation. In recent years, risk stratification has become an important …

The penicillin allergy delabeling program: a multicenter whole-of-hospital health services intervention and comparative effectiveness study

KYL Chua, S Vogrin, S Bury, A Douglas… - Clinical infectious …, 2021 - academic.oup.com
Background Penicillin allergies are associated with inferior patient and antimicrobial
stewardship outcomes. We implemented a whole-of-hospital program to assess the efficacy …

Performance and risks of ChatGPT used in drug information: an exploratory real-world analysis

B Morath, U Chiriac, E Jaszkowski, C Deiß… - European Journal of …, 2024 - ejhp.bmj.com
Objectives To investigate the performance and risk associated with the usage of Chat
Generative Pre-trained Transformer (ChatGPT) to answer drug-related questions. Methods A …

[HTML][HTML] Standards for practical intravenous rapid drug desensitization & delabeling: a WAO committee statement

E Alvarez-Cuesta, R Madrigal-Burgaleta… - World Allergy …, 2022 - Elsevier
Drug hypersensitivity reactions (DHRs) to intravenous drugs can be severe and might leave
patients and doctors in a difficult position where an essential treatment or intervention has to …

[PDF][PDF] Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs

C Mabilat, MF Gros, A Van Belkum… - JAC-Antimicrobial …, 2022 - academic.oup.com
Penicillin allergy, the most frequently reported drug allergy, has been associated with
suboptimal antibiotic therapy, increased antimicrobial resistance, increased rates of …

Differences in beta-lactam and penicillin allergy: beyond the West and focusing on Asia-Pacific

HWF Mak, MHY Yeung, JCY Wong, V Chiang… - Frontiers in …, 2022 - frontiersin.org
Beta-lactam (BL) antibiotic “allergy” labels are common, but often overdiagnosed. Although
much research has been focused on the BL allergy and the delabelling process in the West …