Cytokines act as pleiotropic polypeptides regulating inflammatory and immune responses
through actions on cells. They provide important signals in the pathophysiology of a range of …

One of the most frequent complications in patients with diabetes mellitus is diabetic
nephropathy (DN). At present, it constitutes the first cause of end stage renal disease, and …

Diabetes is a worldwide epidemic that has led to a rise in diabetic kidney disease (DKD).
Over the past two decades, there has been significant clarification of the various pathways …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease and a main
contributing factor for cardiovascular morbidity and mortality in patients with diabetes …

Diabetes mellitus, especially type 2 diabetes, is a public health problem which has reached
epidemic proportions due to the rapidly increasing rates of this disease worldwide. Target …

Diabetic kidney disease is one of the most relevant complications in diabetes mellitus
patients, which constitutes the main cause of end-stage renal disease in the western world …

BACKGROUND: Pentoxifylline is a potential therapeutic agent for diabetic kidney disease
because it has anti-inflammatory, antifibrotic, and hemorheological properties. STUDY …

Conclusions The classical pathogenic vision of diabetes mellitus as a metabolic disorder
has changed in the past years. Inflammation has been demonstrated as an important factor …

Diabetic kidney disease is one of the most frequent complications in patients with diabetes
and constitutes a major cause of end-stage kidney disease. The prevalence of diabetic …

Background Diabetic kidney disease (DKD) is associated with increased morbidity and
mortality, mostly relating to cardiovascular complications. The relevance of inflammation in …