Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …

O-GlcNAcylation—the attachment of O-linked N-acetylglucosamine (O-GlcNAc) moieties to
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …

Bile acids are signaling molecules that coordinately regulate metabolism and inflammation
via the nuclear farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 …

In the mid-1980s, the identification of serine and threonine residues on nuclear and
cytoplasmic proteins modified by a N-acetylglucosamine moiety (O-GlcNAc) via an O …

Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …

Bile acids are the end products of cholesterol catabolism. Hepatic bile acid synthesis
accounts for a major fraction of daily cholesterol turnover in humans. Biliary secretion of bile …

The liver is the central metabolic hub which coordinates nutritional inputs and metabolic
outputs. Food intake releases bile acids which can be sensed by the bile acid receptor FXR …

Bile acids (BAs) are not only digestive surfactants but also important cell signaling
molecules, which stimulate several signaling pathways to regulate some important …

Bile acids are signalling molecules, which activate the transmembrane receptor TGR5 and
the nuclear receptor FXR. BA sequestrants (BAS) complex bile acids in the intestinal lumen …

Over the past decade, it has become apparent that bile acids are involved in a host of
activities beyond their classic functions in bile formation and fat absorption. The identification …