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Precision medicine and the future of cardiovascular diseases: a clinically oriented comprehensive review
Cardiac diseases form the lion's share of the global disease burden, owing to the paradigm
shift to non-infectious diseases from infectious ones. The prevalence of CVDs has nearly …
shift to non-infectious diseases from infectious ones. The prevalence of CVDs has nearly …
Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …
cancer-associated immune system. In recent decades, several investigations have …
An injectable co-assembled hydrogel blocks reactive oxygen species and inflammation cycle resisting myocardial ischemia-reperfusion injury
X Liao, X Song, J Li, L Li, X Fan, Q Qin, C Zhong… - Acta biomaterialia, 2022 - Elsevier
The overproduction of reactive oxygen species (ROS) and burst of inflammation following
cardiac ischemia–reperfusion (I/R) are the leading causes of cardiomyocyte injury …
cardiac ischemia–reperfusion (I/R) are the leading causes of cardiomyocyte injury …
Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics
C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …
[HTML][HTML] An injectable and conductive TEMPOL/polypyrrole integrated peptide co-assembly hydrogel promotes functional maturation of cardiomyocytes for myocardial …
A cell-implantation strategy offers a promising paradigm for cardiac repair after myocardial
infarction (MI). However, the hostile reactive oxygen species (ROS) microenvironment in …
infarction (MI). However, the hostile reactive oxygen species (ROS) microenvironment in …
Baicalin-peptide supramolecular self-assembled nanofibers effectively inhibit ferroptosis and attenuate doxorubicin-induced cardiotoxicity
Doxorubicin, an anthracycline chemotherapeutic agent, elicits a deleterious cardiotoxicity
known as doxorubicin-induced cardiomyopathy (DIC) that circumscribes its chemotherapy …
known as doxorubicin-induced cardiomyopathy (DIC) that circumscribes its chemotherapy …
Nanofibers for the immunoregulation in biomedical applications
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the
selection of appropriate nanomaterials and preparation technology remain some challenges …
selection of appropriate nanomaterials and preparation technology remain some challenges …
Fabrication of blended nanofibrous cardiac patch transplanted with TGF-β3 and human umbilical cord MSCs-derived exosomes for potential cardiac regeneration after …
P **, S Guan, C Ning, T Yang, Y Zhao… - … , Biology and Medicine, 2023 - Elsevier
Acute myocardial infarction (AMI) is a common cardiovascular condition that progressively
results in heart failure. In the present study, we have designed to load transforming growth …
results in heart failure. In the present study, we have designed to load transforming growth …
MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repair
Y Wang, D Wang, C Wu, B Wang, S He, H Wang… - …, 2022 - pmc.ncbi.nlm.nih.gov
Background: The only effective treatment for myocardial infarction (MI) is the timely
restoration of coronary blood flow in the infarcted area, but further reperfusion exacerbates …
restoration of coronary blood flow in the infarcted area, but further reperfusion exacerbates …
[HTML][HTML] Robust drug bioavailability and safety for rheumatoid arthritis therapy using D-amino acids-based supramolecular hydrogels
Long-term use of disease-modifying anti-rheumatic drugs (DMARDs) such as methotrexate
(MTX) shows clinical benefits for rheumatoid arthritis (RA) treatment. However, there are …
(MTX) shows clinical benefits for rheumatoid arthritis (RA) treatment. However, there are …