The autonomic nervous system (ANS), comprised of two primary branches, sympathetic and
parasympathetic nervous system, plays an essential role in the regulation of vascular wall …

Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …

Rationale: Nitric oxide, the classic endothelium-derived relaxing factor (EDRF), acts through
cyclic GMP and calcium without notably affecting membrane potential. A major component of …

Exercise is the most important physiological stimulus for increased myocardial oxygen
demand. The requirement of exercising muscle for increased blood flow necessitates an …

The small arteries (prearteriolar vessels with lumen diameter less than approximately 500
microns) contribute importantly to and participate actively in the regulation of the peripheral …

KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

542 FRANK W. BOOTH AND DONALD B. THOMASON Volume 71 emphasized that
biochemical and physiological adaptations to a changed environment or physiological …

1. A TP-Regulated K+-Channels (KA TP Channels)(a) Single-channel conductance and
voltage dependence (b) Permeability and selectivity (c) Kinetics (d) Effects of. 4 TP (i) …

Blood pressure and tissue perfusion are controlled in part by the level of intrinsic (myogenic)
vascular tone. However, many of the molecular determinants of this response are unknown …

We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv)
channels (Kv1. 1, Kv1. 2, Kv1. 3, Kv1. 5, and Kv3. 1) stably expressed in mammalian cell …