Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis

AD O'brien, VL Tesh, A Donohue-Rolfe… - Pathogenesis of …, 1992 - Springer
Dysentery was well known and clearly described in many ancient texts and histories. The
first step towards the description of the genus Shigella, however, was the identification of …

The piglet as a model for B cell and immune system development

JE Butler, KM Lager, I Splichal, D Francis… - Veterinary immunology …, 2009 - Elsevier
The ability to identify factors responsible for disease in all species depends on the ability to
separate those factors which are environmental from those that are intrinsic. This is …

Associations between Virulence Factors of Shiga Toxin-ProducingEscherichia coli and Disease in Humans

P Boerlin, SA McEwen, F Boerlin-Petzold… - Journal of clinical …, 1999 - journals.asm.org
Associations between known or putative virulence factors of Shiga toxin-producing
Escherichia coli and disease in humans were investigated. Univariate analysis and …

Multiplex PCR for Enterotoxigenic, Attaching and Effacing, and Shiga Toxin-Producing Escherichia coli Strains from Calves

SM Franck, BT Bosworth, HW Moon - Journal of clinical …, 1998 - journals.asm.org
ABSTRACT A multiplex PCR was developed to identify enterotoxigenic, attaching and
effacing, and Shiga toxin-producing Escherichia coli strains by amplifying genes encoding …

Escherichia coli O157: H7: epidemiology, pathogenesis, and methods for detection in food

NV Padhye, MP Doyle - Journal of food protection, 1992 - Elsevier
Escherichia coli O157: H7 is now recognized as an important human pathogen. Illnesses
caused by E. coli O157: H7 infection can range from self-limited, watery diarrhea to life …

Pathogenicity of Escherichia coli O157: H7 in the intestines of neonatal calves

EA Dean-Nystrom, BT Bosworth, WC Cray Jr… - Infection and …, 1997 - journals.asm.org
Cattle are an important reservoir of Shiga toxin-producing enterohemorrhagic Escherichia
coli (EHEC) O157: H7 strains, foodborne pathogens that cause hemorrhagic colitis and …

Bacterial effector binding to ribosomal protein s3 subverts NF-κB function

X Gao, F Wan, K Mateo, E Callegari, D Wang… - PLoS …, 2009 - journals.plos.org
Enteric bacterial pathogens cause food borne disease, which constitutes an enormous
economic and health burden. Enterohemorrhagic Escherichia coli (EHEC) causes a severe …

Protective Effect of Lactobacillus casei Strain Shirota on Shiga Toxin-Producing Escherichia coliO157:H7 Infection in Infant Rabbits

M Ogawa, K Shimizu, K Nomoto… - Infection and …, 2001 - journals.asm.org
We examined colonization patterns of Shiga toxin-producing Escherichia coli (STEC),
concentrations of Shiga toxins (Stxs) and specific immunoglobulin A (lgA) against Stxs and …

Pathogenic and non-pathogenic Escherichia coli colonization and host inflammatory response in a defined microbiota mouse model

ZR Stromberg, A Van Goor… - Disease models & …, 2018 - journals.biologists.com
Most Escherichia coli strains in the human intestine are harmless. However,
enterohemorrhagic E. coli (EHEC) is a foodborne pathogen that causes intestinal disease in …

Experimental verocytotoxemia in rabbits

SE Richardson, TA Rotman, V Jay, CR Smith… - Infection and …, 1992 - journals.asm.org
The clinicopathologic effects of intravenously administered purified verocytotoxin 1 (VT1;
Shiga-like toxin 1) in 2-kg male rabbits was studied. The 50% lethal dose was 0.2 …