Otoferlin as a multirole Ca2+ signaling protein: from inner ear synapses to cancer pathways

JC Leclère, D Dulon - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Humans have six members of the ferlin protein family: dysferlin, myoferlin, otoferlin, fer1L4,
fer1L5, and fer1L6. These proteins share common features such as multiple Ca2+-binding …

Conversations in cochlear implantation: the inner ear therapy of today

G Rauterkus, AK Maxwell, JB Kahane, JJ Lentz… - Biomolecules, 2022 - mdpi.com
As biomolecular approaches for hearing restoration in profound sensorineural hearing loss
evolve, they will be applied in conjunction with or instead of cochlear implants. An …

Robot-assisted electrode insertion in Cochlear implantation controlled by intraoperative Electrocochleography—a pilot study

W Gawęcki, A Balcerowiak, P Podlawska… - Journal of Clinical …, 2022 - mdpi.com
Robotics in otology has been develo** in many directions for more than two decades.
Current clinical trials focus on more accurate stapes surgery, minimally invasive access to …

Human cochlear microstructures at risk of electrode insertion trauma, elucidated in 3D with contrast-enhanced microCT

A Starovoyt, G Pyka, T Putzeys, T Balcaen… - Scientific Reports, 2023 - nature.com
Cochlear implant restores hearing loss through electrical stimulation of the hearing nerve
from within the cochlea. Unfortunately, surgical implantation of this neuroprosthesis often …

Comparative analysis of robotics-assisted and manual insertions of cochlear implant electrode arrays

AD Claussen, SB Shibata, CR Kaufmann… - Otology & …, 2022 - journals.lww.com
Background Whether intracochlear trauma and translocations are two factors that may
contribute to significant variability in CI outcomes remains to be seen. To address this issue …

Evaluation of real-time Intracochlear Electrocochleography for guiding Cochlear implant electrode Array position

R Scheperle, C Etler, J Oleson, C Dunn… - Journal of clinical …, 2023 - mdpi.com
This study evaluates intracochlear electrocochleography (ECochG) for real-time monitoring
during cochlear implantation. One aim tested whether adjusting the recording electrode site …

Anatomically and mechanically accurate scala tympani model for electrode insertion studies

A Starovoyt, E Shaheen, T Putzeys, G Kerckhofs… - Hearing Research, 2023 - Elsevier
The risk of insertion trauma in cochlear implantation is determined by the interplay between
individual cochlear anatomy and electrode insertion mechanics. Whereas patient anatomy …

Medical and Healthcare Robotics: New Paradigms and Recent Advances

O Boubaker - 2023 - books.google.com
Medical and Healthcare Robotics: New Paradigms and Recent Advances provides an
overview and exclusive insights into current trends, the most recent innovations, and …

Drilling accuracy evaluation of a mouldable surgical targeting system for minimally invasive access to anatomic targets in the temporal bone

L Geiger, MG Zuniga, T Lenarz, O Majdani… - European Archives of Oto …, 2023 - Springer
Purpose Minimally invasive cochlear implant surgery using a micro-stereotactic surgical
targeting system with on-site moulding of the template aims for a reliable, less experience …

Robot-assisted and manual Cochlear implantation: an intra-individual study of speech recognition

C Maheo, A Marie, R Torres, J Archutick… - Journal of Clinical …, 2023 - mdpi.com
Cochlear implantation (CI) allows rehabilitation for patients with severe to profound hearing
impairment. Although the use of a robotic assistant provides technical assistance to the …