Global plastics production has reached 380 million metric tons in 2015, with around 40%
used for packaging. Plastic packaging is diverse and made of multiple polymers and …

Background: Pollution–unwanted waste released to air, water, and land by human activity–is
the largest environmental cause of disease in the world today. It is responsible for an …

Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
worldwide. With no Food and Drug Administration approved drugs, current treatment options …

Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Determining protein levels in each tissue and how they compare with RNA levels is
important for understanding human biology and disease as well as regulatory processes …

Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been elucidated to be important risk factors for metabolic diseases …

Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to
bisphenol A (BPA). Moreover, BPA structural analogues (eg BPS, BPF, BPAF), used as BPA …

In 1997, the first in vivo bisphenol A (BPA) study by endocrinologists reported that feeding
BPA to pregnant mice induced adverse reproductive effects in male offspring at the low dose …

One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …