An overview of the public health challenges in diagnosing and controlling human foodborne pathogens

A Elbehiry, A Abalkhail, E Marzouk, AE Elmanssury… - Vaccines, 2023 - mdpi.com
Pathogens found in food are believed to be the leading cause of foodborne illnesses; and
they are considered a serious problem with global ramifications. During the last few …

Norovirus: an overview of virology and preventative measures

N Winder, S Gohar, M Muthana - Viruses, 2022 - mdpi.com
Norovirus (NoV) is an enteric non-enveloped virus which is the leading cause of
gastroenteritis across all age groups. It is responsible for around 200,000 deaths annually …

Human norovirus transmission and evolution in a changing world

M De Graaf, J van Beek, MPG Koopmans - Nature Reviews …, 2016 - nature.com
Norovirus infections are a major cause of gastroenteritis, and outbreaks occur frequently.
Several factors are currently increasing the challenge posed by norovirus infections to …

Dengue virus envelope dimer epitope monoclonal antibodies isolated from dengue patients are protective against Zika virus

JA Swanstrom, JA Plante, KS Plante, EF Young… - MBio, 2016 - journals.asm.org
Zika virus (ZIKV) is a mosquito-borne flavivirus responsible for thousands of cases of severe
fetal malformations and neurological disease since its introduction to Brazil in 2013 …

Norovirus vaccines: current clinical development and challenges

M Tan - Pathogens, 2021 - mdpi.com
Noroviruses are the major viral pathogens causing epidemic and endemic acute
gastroenteritis with significant morbidity and mortality. While vaccines against norovirus …

Vaccination-induced herd immunity: successes and challenges

ML Mallory, LC Lindesmith… - The Journal of allergy and …, 2018 - pmc.ncbi.nlm.nih.gov
The World Health Organization estimates that global vaccination programs save 2–3 million
lives per year by priming the immune system to protect against pathogenic threats that pose …

Prospects and challenges in the development of a norovirus vaccine

NW Cortes-Penfield, S Ramani, MK Estes, RL Atmar - Clinical therapeutics, 2017 - Elsevier
Purpose Norovirus is the leading cause of acute epidemic gastroenteritis among children
under the age of 5 years and adults in the United States and in adults worldwide, accounting …

Environmental surveillance of norovirus genogroups I and II for sensitive detection of epidemic variants

S Kazama, T Miura, Y Masago, Y Konta… - Applied and …, 2017 - journals.asm.org
Sewage samples have been investigated to study the norovirus concentrations in sewage or
the genotypes of noroviruses circulating in human populations. However, the statistical …

[HTML][HTML] Sera antibody repertoire analyses reveal mechanisms of broad and pandemic strain neutralizing responses after human norovirus vaccination

LC Lindesmith, JR McDaniel, A Changela, R Verardi… - Immunity, 2019 - cell.com
Rapidly evolving RNA viruses, such as the GII. 4 strain of human norovirus (HuNoV), and
their vaccines elicit complex serological responses associated with previous exposure …

Immune imprinting drives human norovirus potential for global spread

LC Lindesmith, FAT Boshier, PD Brewer-Jensen, S Roy… - MBio, 2022 - journals.asm.org
Understanding the complex interactions between virus and host that drive new strain
evolution is key to predicting the emergence potential of variants and informing vaccine …