Human temperature regulation under heat stress in health, disease, and injury
1.1. Background During exercise and with exposure to hot climatic conditions, there is
tendency for the human body to store heat and for body temperatures to rise. Changes in …
tendency for the human body to store heat and for body temperatures to rise. Changes in …
Malignant hyperthermia in the post-genomics era: new perspectives on an old concept
S Riazi, N Kraeva, PM Hopkins - Anesthesiology, 2018 - pmc.ncbi.nlm.nih.gov
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle triggered by
volatile anesthetics or succinylcholine. It manifests as a potentially lethal hypermetabolic …
volatile anesthetics or succinylcholine. It manifests as a potentially lethal hypermetabolic …
[HTML][HTML] Rhabdomyolysis: revisited
A Gupta, P Thorson, KR Penmatsa… - The Ulster medical …, 2021 - ncbi.nlm.nih.gov
Rhabdomyolysis (RML) is a pathological entity characterized by symptoms of myalgia,
weakness and dark urine (which is often not present) resulting in respiratory failure and …
weakness and dark urine (which is often not present) resulting in respiratory failure and …
An evidence-based narrative review of the emergency department evaluation and management of rhabdomyolysis
Background Rhabdomyolysis is a medical condition caused by muscle breakdown leading
to potential renal damage. This can result in significant morbidity and mortality if not rapidly …
to potential renal damage. This can result in significant morbidity and mortality if not rapidly …
The etiology of rhabdomyolysis: an interaction between genetic susceptibility and external triggers
N Kruijt, LR van Den Bersselaar… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Rhabdomyolysis is a medical emergency characterized by acute
skeletal muscle breakdown with a sudden rise and subsequent fall of serum creatine kinase …
skeletal muscle breakdown with a sudden rise and subsequent fall of serum creatine kinase …
Metabolic myopathies: a practical approach
JB Lilleker, YS Keh, F Roncaroli, R Sharma… - Practical …, 2018 - pn.bmj.com
Metabolic myopathies are a diverse group of rare genetic disorders and their associated
muscle symptoms may be subtle. Patients may present with indolent myopathic features …
muscle symptoms may be subtle. Patients may present with indolent myopathic features …
Diagnostic biomarkers of muscle injury and exertional rhabdomyolysis
Early recognition of muscle injury, up to development of exertional rhabdomyolysis (ER), is
essential for many clinical and practical reasons, such as planning the suitable period of …
essential for many clinical and practical reasons, such as planning the suitable period of …
C-reactive protein is elevated only in high creatine kinase responders to muscle damaging exercise
The purpose of this study was to investigate if exertional rhabdomyolysis induced by an
acute bout of plyometric exercise in untrained individuals was associated with histological …
acute bout of plyometric exercise in untrained individuals was associated with histological …
Clinical characteristics and risk factors associated with acute kidney injury inpatient with exertional heatstroke: an over 10-year intensive care survey
M Wu, C Wang, Z Liu, L Zhong, B Yu, B Cheng… - Frontiers in …, 2021 - frontiersin.org
Background: Exertional heat stroke (EHS) is a life-threatening injury that can lead to acute
kidney injury (AKI). The clinical characteristics of and risk factors for EHS complicated with …
kidney injury (AKI). The clinical characteristics of and risk factors for EHS complicated with …
Muscle biopsy: what and why and when?
J Walters, A Baborie - Practical Neurology, 2020 - pn.bmj.com
Skeletal muscle biopsy remains an important investigative tool in the diagnosis of a variety
of muscle disorders. Traditionally, someone with a limb-girdle muscle weakness, myopathic …
of muscle disorders. Traditionally, someone with a limb-girdle muscle weakness, myopathic …