Smart cell culture systems: Integration of sensors and actuators into microphysiological systems

MM Modena, K Chawla, PM Misun… - ACS chemical …, 2018 - ACS Publications
Technological advances in microfabrication techniques in combination with organotypic cell
and tissue models have enabled the realization of microphysiological systems capable of …

The latest advances on nonlinear insulator-based electrokinetic microsystems under direct current and low-frequency alternating current fields: a review

BH Lapizco-Encinas - Analytical and Bioanalytical Chemistry, 2022 - Springer
This review article presents an overview of the evolution of the field of insulator-based
dielectrophoresis (iDEP); in particular, it focuses on insulator-based electrokinetic (iEK) …

AC electric field induced dipole-based on-chip 3D cell rotation

P Benhal, JG Chase, P Gaynor, B Oback, W Wang - Lab on a Chip, 2014 - pubs.rsc.org
The precise rotation of suspended cells is one of the many fundamental manipulations used
in a wide range of biotechnological applications such as cell injection and enucleation in …

Microfluidic laboratories for C. elegans enhance fundamental studies in biology

NA Bakhtina, JG Korvink - Rsc Advances, 2014 - pubs.rsc.org
The in vivo analysis of a small multicellular organism such as the nematode Caenorhabditis
elegans, enables fundamental biomedical and environmental studies of a complete …

Exploring living multicellular organisms, organs, and tissues using microfluidic systems

V Sivagnanam, MAM Gijs - Chemical reviews, 2013 - ACS Publications
Lab-on-a-chip (LoC) systems allow the implementation of benchtop analytical
methods/protocols using low reagent volumes, short processing times, and this potentially at …

Experimental and theoretical study of dielectrophoretic particle trap** in arrays of insulating structures: Effect of particle size and shape

MA Saucedo‐Espinosa, BH Lapizco‐Encinas - Electrophoresis, 2015 - Wiley Online Library
Insulator‐based dielectrophoresis (iDEP) employs insulating structures embedded in a
microchannel to produce electric field gradients. This contribution presents a detailed …

Studying Parkinson's disease using Caenorhabditis elegans models in microfluidic devices

K Youssef, A Tandon, P Rezai - Integrative Biology, 2019 - academic.oup.com
Parkinson's disease (PD) is a progressive neurological disorder associated with the loss of
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …

Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

H Yuan, W Yuan, S Duan, K Jiao, Q Zhang… - Cyborg and Bionic …, 2023 - spj.science.org
Caenorhabditis elegans (C. elegans) has been a popular model organism for several
decades since its first discovery of the huge research potential for modeling human diseases …

A Fully Automated Microfluidic Femtosecond Laser Axotomy Platform for Nerve Regeneration Studies in C. elegans

SK Gokce, SX Guo, N Ghorashian, WN Everett… - PloS one, 2014 - journals.plos.org
Femtosecond laser nanosurgery has been widely accepted as an axonal injury model,
enabling nerve regeneration studies in the small model organism, Caenorhabditis elegans …

Nonlinear Electrokinetic Methods of Particles and Cells

BH Lapizco-Encinas - Annual Review of Analytical Chemistry, 2024 - annualreviews.org
Nonlinear electrokinetic phenomena offer label-free, portable, and robust approaches for
particle and cell assessment, including selective enrichment, separation, sorting, and …