The cluster glycoside effect

JJ Lundquist, EJ Toone - Chemical reviews, 2002 - ACS Publications
Myriad biological communication events achieve the requisite level of specificity by
exploiting the rich structural and functional diversity of glycoconjugates. Although a wide …

Glycopolymer nanobiotechnology

Y Miura, Y Hoshino, H Seto - Chemical reviews, 2016 - ACS Publications
Molecular recognition plays an important role in living systems. 1, 2 Representative
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …

A nanoscale optical biosensor: sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver …

AJ Haes, RP Van Duyne - Journal of the American Chemical …, 2002 - ACS Publications
Triangular silver nanoparticles (∼ 100 nm wide and 50 nm high) have remarkable optical
properties. In particular, the peak extinction wavelength, λmax of their localized surface …

Synthetic multivalent ligands as probes of signal transduction

LL Kiessling, JE Gestwicki… - Angewandte Chemie …, 2006 - Wiley Online Library
Cell‐surface receptors acquire information from the extracellular environment and
coordinate intracellular responses. Many receptors do not operate as individual entities, but …

Influencing receptor− ligand binding mechanisms with multivalent ligand architecture

JE Gestwicki, CW Cairo, LE Strong… - Journal of the …, 2002 - ACS Publications
Multivalent ligands can function as inhibitors or effectors of biological processes. Potent
inhibitory activity can arise from the high functional affinities of multivalent ligand− receptor …

Glycopolymer probes of signal transduction

LL Kiessling, JC Grim - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycans are key participants in biological processes ranging from reproduction to cellular
communication to infection. Revealing glycan roles and the underlying molecular …

A unified view of propagating and localized surface plasmon resonance biosensors

AJ Haes, RP Van Duyne - Analytical and bioanalytical chemistry, 2004 - Springer
The intense colors of noble metal nanoparticles have inspired artists and fascinated
scientists for hundreds of years. In this review, we describe refractive index sensing …

High-sensitivity analytical approaches for the structural characterization of glycoproteins

WR Alley Jr, BF Mann, MV Novotny - Chemical reviews, 2013 - ACS Publications
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Self-assembled monolayers and polymer brushes in biotechnology: current applications and future perspectives

W Senaratne, L Andruzzi, CK Ober - Biomacromolecules, 2005 - ACS Publications
The chemistry and topography of a surface affect biological response and are of
fundamental importance, especially when living systems encounter synthetic surfaces. Most …

Synthesis of neoglycopolymers by a combination of “click chemistry” and living radical polymerization

V Ladmiral, G Mantovani, GJ Clarkson… - Journal of the …, 2006 - ACS Publications
The synthesis of novel well-defined alkyne side chain functional polymers featuring narrow
molecular weight distributions (PDI= 1.09− 1.17) by living radical polymerization is …