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Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint …
S Soussan, G Pupier, I Cremer, PE Joubert… - Frontiers in …, 2024 - frontiersin.org
The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet
crucial aspect of cancer biology. Tumor microenvironment often exhibits autoimmune …
crucial aspect of cancer biology. Tumor microenvironment often exhibits autoimmune …
Mechanisms of tertiary lymphoid structure formation: cooperation between inflammation and antigenicity
To mount an effective anti-tumor immune response capable of controlling or eliminating
disease, sufficient numbers of lymphocytes must be recruited to malignant tissue and …
disease, sufficient numbers of lymphocytes must be recruited to malignant tissue and …
Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma
L Rupp, I Dietsche, M Kießler, U Sommer… - Frontiers in …, 2024 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages and
associated with early distant metastasis and poor survival. Besides clinical factors, the tumor …
associated with early distant metastasis and poor survival. Besides clinical factors, the tumor …
The Role of B Cells in Solid Tumors
H Silva, D Sherwin… - Annual Review of Cancer …, 2024 - annualreviews.org
A surge of recent studies have identified B cells as pivotal contributors to sha** the tumor
microenvironment (TME) within solid tumors. B cells can both directly and indirectly …
microenvironment (TME) within solid tumors. B cells can both directly and indirectly …
[HTML][HTML] B cells and tertiary lymphoid structures in tumors: immunity cycle, clinical impact, and therapeutic applications
X Wu, Q Huang, X Chen, B Zhang, J Liang… - Theranostics, 2025 - pmc.ncbi.nlm.nih.gov
Tumorigenesis involves a multifaceted and heterogeneous interplay characterized by
perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as …
perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as …
Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic …
Pancreatic adenocarcinoma (PDAC) is a rapidly progressing cancer that responds poorly to
immunotherapies. Intratumoral tertiary lymphoid structures (TLS) have been associated with …
immunotherapies. Intratumoral tertiary lymphoid structures (TLS) have been associated with …
Deciphering and harnessing the role of tumour-infiltrating B cells in anti-tumour immunity
AC Banville - 2024 - open.library.ubc.ca
Current cancer immunotherapies primarily leverage prognostically favourable tumour-
infiltrating T cells (TIL-Ts); however, optimal anti-tumour immunity additionally requires …
infiltrating T cells (TIL-Ts); however, optimal anti-tumour immunity additionally requires …