Abstract Beta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …

Diabetes is one of the most detrimental diseases affecting the human life because it can
initiate several other afflictions such as liver damage, kidney malfunctioning, and cardiac …

Long-wavelength emission with high contrast toward species of interest is highly desired for
fluorescence imaging in living objects. Herein, we proposed an exquisite enzyme-regulated …

Since hydrogen sulfide (H 2 S) plays a vital role in physiological functions, it is significant to
assess the dynamic levels of H 2 S in cellular levels and real samples. Nonetheless, a …

Organic fluorescent materials are widely used in various fields, including OLEDs, organic
solar cells, and bio-imaging. However, designing and synthesizing new fluorescent organic …

Real-time monitoring of lysosomal pH is critical for understanding lysosome-related
biological processes and diseases, but few lysosome probes can achieve this response …

Mitochondria and lysosomes are pivotal intracellular organelles, and the injury or
dysfunction of these organelles can trigger a range of pathological processes. Early …

Although oxidative stress processes based on reactive oxygen species have been the
research focus, analyzing this phenomenon at the single-cell level is challenging. A …

In situ real-time quantitative monitoring pH fluctuation in complex living systems is vitally
significant. In the current work, a ratiometric near-infrared (NIR) probe (MCyOH) was …

Real-time optical sensing of mercury has been developed rapidly in recent years but
remains challenging such as bearing background interference. Herein, a Hg 2+ and base …