The song remains the same. The lab bench dilemma of using shaken flasks in microbial biotransformation experiments

NS de Oliveira, GPL da Silva, O Furlan… - Biocatalysis and …, 2024 - Taylor & Francis
Microbial biotransformation is valuable for obtaining pharmaceutical, nutritional, and
cosmetical potential molecules. Basically, for its realization, only a parental molecule, a …

Efforts toward ambergris biosynthesis

N He, H Yu, L Ye - Chem & Bio Engineering, 2024 - ACS Publications
Ambergris is a very rare and highly valued fauna natural perfume. Its main component,
ambrein, undergoes oxidative degradation to produce ambroxide, forming the unique …

Construction of an artificial microbial consortium for green production of (−)-Ambroxide

N He, DF Li, HW Yu, LD Ye - ACS Sustainable Chemistry & …, 2023 - ACS Publications
(−)-Ambroxide is a key ingredient of the fauna natural perfume ambergris, which is currently
mainly supplied by the semi-synthetic route using plant-extracted sclareol as the raw …

Probing the Biotransformation Process of Sclareol by Resting Cells of Hyphozyma roseonigra

M Diao, C Li, J Li, J Lu, N **e - Journal of Agricultural and Food …, 2022 - ACS Publications
Sclareol glycol is a key starting material with significant market interest for synthesizing high-
value ambroxide, a sustainable substitute for ambergris in high-end fragrances. Sclareol …

Metabolomics-Guided Analysis of the Biocatalytic Conversion of Sclareol to Ambradiol by Hyphozyma roseoniger

EN Ncube, PA Steenkamp, CW van der Westhuyzen… - Catalysts, 2022 - mdpi.com
The biocatalytic conversion of sclareol to ambradiol, a valuable component in the fragrance
industry, using whole-cell biotransformation by the dimorphic yeast Hyphozyma roseoniger …

[HTML][HTML] Untargeted Metabolomics Exploration of the Growth Stage-Dependent Chemical Space of the Sclareol-Converting Biocatalyst Hyphozyma roseonigra

EN Ncube, L Sitole, PA Steenkamp, LH Steenkamp… - Catalysts, 2022 - mdpi.com
Hyphozyma roseonigra is a dimorphic yeast used as a biocatalyst to convert sclareol, a plant
diterpenoid to ambradiol. The latter is an intermediate in the synthesis of ambrafuran, a high …