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Gut microbiota and rheumatoid arthritis: From pathogenesis to novel therapeutic opportunities
T Zhao, Y Wei, Y Zhu, Z **e, Q Hai, Z Li… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints.
Microbial infection is considered a crucial inducer of RA. Alterations in the composition of …
Microbial infection is considered a crucial inducer of RA. Alterations in the composition of …
Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
The gut–joint axis in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder that primarily
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …
Microbial dysbiosis in the gut drives systemic autoimmune diseases
WK Mousa, F Chehadeh, S Husband - Frontiers in immunology, 2022 - frontiersin.org
Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …
crucial to the development and maturation of our immune system and to maintain gut …
[HTML][HTML] Molecular mimicry and autoimmunity
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …
Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
Microbial metabolites are known to modulate immune responses of the host. The main
metabolites derived from microbial fermentation of dietary fibers in the intestine, short-chain …
metabolites derived from microbial fermentation of dietary fibers in the intestine, short-chain …
Crosstalk between gut microbiota and innate immunity and its implication in autoimmune diseases
The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …
The role of the gut microbiome in systemic inflammatory disease
The role of the gut microbiome in models of inflammatory and autoimmune disease is now
well characterized. Renewed interest in the human microbiome and its metabolites, as well …
well characterized. Renewed interest in the human microbiome and its metabolites, as well …
[HTML][HTML] Role of microbiota short-chain fatty acids in the pathogenesis of autoimmune diseases
There is emerging evidence that microbiota and its metabolites play an important role in
helath and diseases. In this regard, gut microbiota has been found as a crucial component …
helath and diseases. In this regard, gut microbiota has been found as a crucial component …
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes
Musculoskeletal diseases affect up to 20% of adults worldwide. The gut microbiome has
been implicated in inflammatory conditions, but large-scale metagenomic evaluations have …
been implicated in inflammatory conditions, but large-scale metagenomic evaluations have …