The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
CCL2: An important cytokine in normal and pathological pregnancies: A review
Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …
integral chemotactic factor which recruits macrophages for the immune response. Together …
Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2
Pregnant women represent a high-risk population for severe/critical COVID-19 and mortality.
However, the maternal-fetal immune responses initiated by SARS-CoV-2 infection, and …
However, the maternal-fetal immune responses initiated by SARS-CoV-2 infection, and …
[HTML][HTML] A single-cell atlas of the myometrium in human parturition
Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing
Labor is a complex physiological process requiring a well-orchestrated dialogue between
the mother and fetus. However, the cellular contributions and communications that facilitate …
the mother and fetus. However, the cellular contributions and communications that facilitate …
Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
Background Fetal inflammatory response mediated by the influx of immune cells and
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
Innate and adaptive immune systems in physiological and pathological pregnancy
Simple Summary Pregnancy is a continually evolving process with many moving parts that
must be tightly regulated on both the maternal and fetal sides to ensure its success. A …
must be tightly regulated on both the maternal and fetal sides to ensure its success. A …
The molecular mechanisms of HLA-G regulatory function on immune cells during early pregnancy
J Mao, Y Feng, X Zhu, F Ma - Biomolecules, 2023 - mdpi.com
Human leukocyte antigen-G (HLA-G) is a non-classical human major histocompatibility
complex (MHC-I) molecule with the membrane-bound and soluble types. HLA-G is primarily …
complex (MHC-I) molecule with the membrane-bound and soluble types. HLA-G is primarily …
The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study
Background: Preterm birth is the leading cause of neonatal morbidity and mortality
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …
Single-cell immunobiology of the maternal–fetal interface
Pregnancy success requires constant dialogue between the mother and develo**
conceptus. Such crosstalk is facilitated through complex interactions between maternal and …
conceptus. Such crosstalk is facilitated through complex interactions between maternal and …