During their development, cancers acquire several functional capabilities, which are defined
as the hallmarks of cancer. For a deeper understanding of the hallmarks of cancer, and …

MRI is an essential tool in breast imaging, with multiple established indications. Dynamic
contrast-enhanced MRI (DCE-MRI) is the backbone of any breast MRI protocol and has an …

Magnetic resonance imaging (MRI) has been proposed to have a role in predicting final
pathologic response when undertaken early during neoadjuvant chemotherapy (NAC) in …

Breast MRI has increased in popularity over the past two decades due to evidence for its
high sensitivity for cancer detection. Current clinical MRI approaches rely on the use of a …

Purpose The purpose of this pilot study is to determine (1) if early changes in both
semiquantitative and quantitative DCE‐MRI parameters, observed after the first cycle of …

Magnetic resonance imaging (MRI) is the most sensitive imaging modality for breast cancer
detection. This systematic review investigated the role of quantitative MRI features in …

Cancer remains a global killer alongside cardiovascular disease. A better understanding of
cancer biology has transformed its management with an increasing emphasis on a …

Purpose: To determine whether a simple noninvasive method of assessing tumor
oxygenation is feasible in the clinical setting and can provide useful, potentially predictive …

Purpose: Multiple cancers harbor genetic aberrations that impact AKT signaling. MK-2206 is
a potent pan-AKT inhibitor with a maximum tolerated dose (MTD) previously established at …

Abstract Objectives Triple-negative (ER-/PR-/HER2-) breast carcinomas (TNBC) are
aggressive tumours with underexplored imaging features. This study investigates whether …