Artificial intelligence in neuro-oncology: advances and challenges in brain tumor diagnosis, prognosis, and precision treatment

S Khalighi, K Reddy, A Midya, KB Pandav… - NPJ precision …, 2024 - nature.com
This review delves into the most recent advancements in applying artificial intelligence (AI)
within neuro-oncology, specifically emphasizing work on gliomas, a class of brain tumors …

Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours

C Horbinski, T Berger, RJ Packer, PY Wen - Nature Reviews Neurology, 2022 - nature.com
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

Unified rhombic lip origins of group 3 and group 4 medulloblastoma

KS Smith, L Bihannic, BL Gudenas, P Haldipur, R Tao… - Nature, 2022 - nature.com
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into
biologically distinct subgroups, suggesting that a personalized approach to therapy would …

The whole-genome landscape of medulloblastoma subtypes

PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt… - Nature, 2017 - nature.com
Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose
debilitating effects on the develo** child, and highlight the need for molecularly targeted …

Medulloblastoma in the age of molecular subgroups: a review: JNSPG 75th Anniversary Invited Review Article

K Juraschka, MD Taylor - Journal of Neurosurgery: Pediatrics, 2019 - thejns.org
Medulloblastoma is the most common pediatric malignant brain tumor. Advances in
molecular profiling have uncovered significant heterogeneity among medulloblastomas and …

Medulloblastoma

PA Northcott, GW Robinson, CP Kratz… - Nature reviews Disease …, 2019 - nature.com
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours
of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog …

Second-generation molecular subgrou** of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

T Sharma, EC Schwalbe, D Williamson, M Sill… - Acta …, 2019 - Springer
In 2012, an international consensus paper reported that medulloblastoma comprises four
molecular subgroups (WNT, SHH, Group 3, and Group 4), each associated with distinct …

Risk stratification of childhood medulloblastoma in the molecular era: the current consensus

V Ramaswamy, M Remke, E Bouffet, S Bailey… - Acta …, 2016 - Springer
Historical risk stratification criteria for medulloblastoma rely primarily on clinicopathological
variables pertaining to age, presence of metastases, extent of resection, histological …

Medulloblastomics revisited: biological and clinical insights from thousands of patients

V Hovestadt, O Ayrault, FJ Swartling… - Nature Reviews …, 2020 - nature.com
Medulloblastoma, a malignant brain tumour primarily diagnosed during childhood, has
recently been the focus of intensive molecular profiling efforts, profoundly advancing our …