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Artificial intelligence in neuro-oncology: advances and challenges in brain tumor diagnosis, prognosis, and precision treatment
This review delves into the most recent advancements in applying artificial intelligence (AI)
within neuro-oncology, specifically emphasizing work on gliomas, a class of brain tumors …
within neuro-oncology, specifically emphasizing work on gliomas, a class of brain tumors …
Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …
Although the previous edition of this classification was published just 5 years earlier, in …
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into
biologically distinct subgroups, suggesting that a personalized approach to therapy would …
biologically distinct subgroups, suggesting that a personalized approach to therapy would …
The whole-genome landscape of medulloblastoma subtypes
Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose
debilitating effects on the develo** child, and highlight the need for molecularly targeted …
debilitating effects on the develo** child, and highlight the need for molecularly targeted …
Medulloblastoma in the age of molecular subgroups: a review: JNSPG 75th Anniversary Invited Review Article
Medulloblastoma is the most common pediatric malignant brain tumor. Advances in
molecular profiling have uncovered significant heterogeneity among medulloblastomas and …
molecular profiling have uncovered significant heterogeneity among medulloblastomas and …
Medulloblastoma
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours
of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog …
of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog …
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study
Background International consensus recognises four medulloblastoma molecular
subgroups: WNT (MB WNT), SHH (MB SHH), group 3 (MB Grp3), and group 4 (MB Grp4) …
subgroups: WNT (MB WNT), SHH (MB SHH), group 3 (MB Grp3), and group 4 (MB Grp4) …
Second-generation molecular subgrou** of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
In 2012, an international consensus paper reported that medulloblastoma comprises four
molecular subgroups (WNT, SHH, Group 3, and Group 4), each associated with distinct …
molecular subgroups (WNT, SHH, Group 3, and Group 4), each associated with distinct …
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus
Historical risk stratification criteria for medulloblastoma rely primarily on clinicopathological
variables pertaining to age, presence of metastases, extent of resection, histological …
variables pertaining to age, presence of metastases, extent of resection, histological …
Medulloblastomics revisited: biological and clinical insights from thousands of patients
Medulloblastoma, a malignant brain tumour primarily diagnosed during childhood, has
recently been the focus of intensive molecular profiling efforts, profoundly advancing our …
recently been the focus of intensive molecular profiling efforts, profoundly advancing our …